Evidence map›Paper›PMID 25544942›Full record

ArticleBioMed research international2014

Changing interdigestive migrating motor complex in rats under acute liver injury.

Mei Liu, Su-Jun Zheng, Weihong Xu, Jianying Zhang, Yu Chen, Zhongping Duan

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Mei LiuArtificial Liver Center, Beijing You'an Hospital, Capital Medical University, Beijing 100069, China ; Department of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79968, USA.ORCID 0000-0003-2740-6281
Su-Jun ZhengArtificial Liver Center, Beijing You'an Hospital, Capital Medical University, Beijing 100069, China.
Weihong XuDepartment of Rheumatology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China.
Jianying ZhangDepartment of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79968, USA.
Yu ChenArtificial Liver Center, Beijing You'an Hospital, Capital Medical University, Beijing 100069, China.
Zhongping DuanArtificial Liver Center, Beijing You'an Hospital, Capital Medical University, Beijing 100069, China.
Capital Medical University · CNThe University of Texas at El Paso · USSecond Affiliated Hospital of Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastrointestinal motility disorder is a major clinical manifestation of acute liver injury, and interdigestive migrating motor complex (MMC) is an important indicator. We investigated the changes and characteristics of MMC in rats with acute liver injury. Acute liver injury was created by d-galactosamine, and we recorded the interdigestive MMC using a multichannel physiological recorder and compared the indexes of interdigestive MMC. Compared with normal controls, antral MMC Phase I duration was significantly prolonged and MMC Phase III duration was significantly shortened in the rats with acute liver injury. The duodenal MMC cycle and MMC Phases I and IV duration were significantly prolonged and MMC Phase III duration was significantly shortened in the rats with acute liver injury. The jejunal MMC cycle and MMC Phases I and IV duration were significantly prolonged and MMC Phase III duration was significantly shortened in the rats with acute liver injury compared with normal controls. Compared with the normal controls, rats with acute liver injury had a significantly prolonged interdigestive MMC cycle, related mainly to longer MMC Phases I and IV, shortened MMC Phase III, and MMC Phase II characterized by increased migrating clustered contractions, which were probably major contributors to the gastrointestinal motility disorders.

Indexed as

Gastrointestinal MotilityMyoelectric Complex, MigratingAnimalsChemical and Drug Induced Liver InjuryDigestionDuodenumGalactosamineHumansLiverRatsGalactosamine

Identifiers

PMID25544942
PMCPMC4228720
OpenAlexW2077758708

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.