Evidence map›Paper›PMID 25544866›Full record

ArticleCurrent cardiovascular risk reports2014

Hypertension Treatment for Patients with Advanced Chronic Kidney Disease.

Arjun D Sinha, Rajiv Agarwal

Open access · greenAbstract read
In one paragraph

Article in Current cardiovascular risk reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Pro: Ambulatory blood pressure should be used in all patients on hemodialysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Arjun D SinhaDivision of Nephrology, Indianapolis, IN ; Richard L. Roudebush VA Medical Center, Indianapolis, IN.
Rajiv AgarwalDivision of Nephrology, Indianapolis, IN ; Richard L. Roudebush VA Medical Center, Indianapolis, IN.
Indiana University · USIndiana University School of Medicine

Funding

Hypertension in Hemodialysis PatientsR01DK062030 · NIDDK · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI AGARWAL, RAJIV · 2003 to 2013
$3.8M
ChLorthalidone In Chronic Kidney Disease (CLICK) StudyR01HL126903 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI AGARWAL, RAJIV · 2016 to 2020
$3.2M
Masked Hypertension in Chronic Kidney DiseaseI01CX000829 · VA · RLR VA MEDICAL CENTER · PI AGARWAL, RAJIV · 2013 to 2016
–
CSRD VA I01 CX000829NHLBI NIH HHS R01 HL126903NIDDK NIH HHS R01 DK062030
6 · The paper itself

Abstract

Chronic kidney disease is common and frequently complicated with hypertension. As a major modifiable risk factor for cardiovascular disease in this high risk population, treatment of hypertension in chronic kidney disease is of paramount importance. We review the epidemiology and pathogenesis of hypertension in chronic kidney disease and then update the latest study results for treatment including salt restriction, invasive endovascular procedures, and pharmacologic therapy. Recent trials draw into question the efficacy of renal artery stenting or renal denervation for hypertension in chronic kidney disease, as well as renin-angiotensin-aldosterone system blockade as first line therapy of hypertension in end stage renal disease. Positive trial results reemphasize salt restriction and challenge the prevailing prejudice against the use of thiazide-like diuretics in advanced chronic kidney disease. Lastly, clinical practice guidelines are trending away from recommending tight blood pressure control in chronic kidney disease.

Indexed as

chronic kidney diseaseend stage renal diseasehemodialysishypertensionresistant hypertension

Identifiers

PMID25544866
PMCPMC4274947
OpenAlexW2006433058

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.