Evidence map›Paper›PMID 25544781›Full record

ArticlePeriodicum biologorum2014

Neurological and psychiatric disorders as a neuroglial failure.

Alexei Verkhratsky, Vladimir Parpura

Abstract read
In one paragraph

Article in Periodicum biologorum, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. The Astrogenic Balance in the Aging Brain.Current neuropharmacology · 2021
    Review
  5. Microglial Density Alters Measures of Axonal Integrity and Structural Connectivity.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2020
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alexei VerkhratskyFaculty of Life Sciences, The University of Manchester, Manchester, M13 9PT, UK ; Achucarro Center for Neuroscience, IKERBASQUE, Basque Foundation for Science, 48011 Bilbao, Spain ; University of Nizhny Novgorod, Nizhny Novgorod 603022, Russia.
Vladimir ParpuraDepartment of Neurobiology, Center for Glial Biology in Medicine, Atomic Force Microscopy & Nanotechnology Laboratories, Civitan International Research Center, Evelyn F. McKnight Brain Institute, University of Alabama, Birmingham, AL 35294, USA ; Department of Biotechnology, University or Rijeka, 51000 Rijeka, Croatia.

Funding

The Role of Astroglia in the Enteric Nervous System and Gut FunctionR21HD078678 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI PARPURA, VLADIMIR · 2014 to 2015
$400k
NICHD NIH HHS R21 HD078678
6 · The paper itself

Abstract

Neuroglia are a diverse non-neuronal population of cells in the central and peripheral nervous system. These cells have a variety of functions that can all be summed up as the maintenance of homeostasis of the nervous system. It is the loss of homeostasis that represents the culprit of all disorders. Thus, neuroglia can be envisioned as the pivotal element in all neural disorders, be that neurological or psychiatric. In this review, we discuss the role of glia in homeostasis and defence of the nervous system as well as changes in the morpho-functional characteristics of these cells in various disorders.

Indexed as

astrocytemicroglianeurodegenerationneuroglianeurological diseasesNG2 gliaoligodendrocytepsychiatric diseasesreactive gliosis

Identifiers

PMID25544781
PMCPMC4276339

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.