ArticleHeart & lung : the journal of critical care
Stratifying patients at the risk of heart failure hospitalization using existing device diagnostic thresholds.
Article in Heart & lung : the journal of critical care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Remote monitoring in patients with heart failure with cardiac implantable electronic devices: a systematic review and meta-analysis.Open heart · 2022Pooled it
- Measuring Physical Activity With Implanted Cardiac Devices: A Systematic Review.Journal of the American Heart Association · 2018Pooled it
- Prospective evaluation of integrated device diagnostics for heart failure management: results of the TRIAGE-HF study.ESC heart failure · 2018Trial
- Clinical and financial impact of sleep disordered breathing on heart failure admissions.Sleep & breathing = Schlaf & Atmung · 2023Article
- Accelerometer-assessed physical behavior and the association with clinical outcomes in implantable cardioverter-defibrillator recipients: A systematic review.Cardiovascular digital health journal · 2022Review
- Clinical utility of CorVue intrathoracic impedance alert with device-measured physical activity in predicting heart failure events.Heart and vessels · 2021Article
- Prediction of heart failure hospitalizations based on the direct measurement of intrathoracic impedance.ESC heart failure · 2020Article
- Incremental Value of Implantable Cardiac Device Diagnostic Variables Over Clinical Parameters to Predict Mortality in Patients With Mild to Moderate Heart Failure.Journal of the American Heart Association · 2019Article
- Redefining the role of biomarkers in heart failure trials: expert consensus document.Heart failure reviews · 2017Review
- Prediction of All-Cause Mortality Based on the Direct Measurement of Intrathoracic Impedance.Circulation. Heart failure · 2016Article
- Evolution from electrophysiologic to hemodynamic monitoring: the story of left atrial and pulmonary artery pressure monitors.Frontiers in physiology · 2015Review
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundHeart failure hospitalizations (HFHs) cost the US health care system ∼$20 billion annually. Identifying patients at risk of HFH to enable timely intervention and prevent expensive hospitalization remains a challenge. Implantable cardioverter defibrillators (ICDs) and cardiac resynchronization devices with defibrillation capability (CRT-Ds) collect a host of diagnostic parameters that change with HF status and collectively have the potential to signal an increasing risk of HFH. These device-collected diagnostic parameters include activity, day and night heart rate, atrial tachycardia/atrial fibrillation (AT/AF) burden, mean rate during AT/AF, percent CRT pacing, number of shocks, and intrathoracic impedance. There are thresholds for these parameters that when crossed trigger a notification, referred to as device observation, which gets noted on the device report. We investigated if these existing device observations can stratify patients at varying risk of HFH.
methodsWe analyzed data from 775 patients (age: 69 ± 11 year, 68% male) with CRT-D devices followed for 13 ± 5 months with adjudicated HFHs. HFH rate was computed for increasing number of device observations. Data were analyzed by both excluding and including intrathoracic impedance. HFH risk was assessed at the time of a device interrogation session, and all the data between previous and current follow-up sessions were used to determine the HFH risk for the next 30 days.
results2276 follow-up sessions in 775 patients were evaluated with 42 HFHs in 37 patients. Percentage of evaluations that were followed by an HFH within the next 30 days increased with increasing number of device observations. Patients with 3 or more device observations were at 42× HFH risk compared to patients with no device observation. Even after excluding intrathoracic impedance, the remaining device parameters effectively stratified patients at HFH risk.
conclusionAvailable device observations could provide an effective method to stratify patients at varying risk of heart failure hospitalization.
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