Evidence map›Paper›PMID 25543008›Full record

ReviewDrug discovery today2015

Silver nanoparticles: synthesis, properties, and therapeutic applications.

Liuya Wei, Jingran Lu, Huizhong Xu, Atish Patel, Zhe-Sheng Chen, Guofang Chen

Open access · greenAbstract readReview
In one paragraph

Review in Drug discovery today, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 243 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
243citing papers in PubMed, 1 pooled it
17.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

243 citing papers in PubMed, 1 synthesis or guideline pooled it, 951 citations in OpenAlex.

  1. Nanoparticles as Alternatives for the Control ofFrontiers in veterinary science · 2021
    Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Clinical translation and landscape of copper nanoparticles.Drug delivery and translational research · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Green Synthesis of Silver Nanoparticles FromInternational journal of microbiology · 2026
    Article
  17. Article
  18. Review
  19. Article
  20. Article

183 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Liuya WeiSchool of Pharmacy, Weifang Medical University, Weifang 261053, People's Republic of China; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St John's University, Queens, NY 11439, USA.
Jingran LuDepartment of Chemistry, St John's College of Liberal Arts and Science, St John's University, Queens, NY 11439, USA.
Huizhong XuDepartment of Physics, St John's College of Liberal Arts and Science, St John's University, Queens, NY 11439, USA.
Atish PatelDepartment of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St John's University, Queens, NY 11439, USA.
Zhe-Sheng ChenDepartment of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St John's University, Queens, NY 11439, USA. Electronic address: chenz@stjohns.edu.
Guofang ChenDepartment of Chemistry, St John's College of Liberal Arts and Science, St John's University, Queens, NY 11439, USA. Electronic address: gfchen08@yahoo.com.
St. John's University · USSt. John's College · US

Funding

Targeting MRP7 to Overcome Drug Resistance for Ovarian Cancer Therapy by TaxanesR15CA143701 · NCI · ST. JOHN'S UNIVERSITY · PI CHEN, ZHE-SHENG · 2010 to 2010
$245k
NCI NIH HHS R15 CA143701
6 · The paper itself

Abstract

Silver nanoparticles (AgNPs) have been widely used in biomedical fields because of their intrinsic therapeutic properties. Here, we introduce methods of synthesizing AgNPs and discuss their physicochemical, localized surface plasmon resonance (LSPR) and toxicity properties. We also review the impact of AgNPs on human health and the environment along with the underlying mechanisms. More importantly, we highlight the newly emerging applications of AgNPs as antiviral agents, photosensitizers and/or radiosensitizers, and anticancer therapeutic agents in the treatment of leukemia, breast cancer, hepatocellular carcinoma, lung cancer, and skin and/or oral carcinoma.

Indexed as

AnimalsAntineoplastic AgentsAntiviral AgentsHumansMetal NanoparticlesNanomedicinePhotosensitizing AgentsRadiation-Sensitizing AgentsRisk AssessmentSilver CompoundsSurface PropertiesTreatment OutcomeAntineoplastic AgentsAntiviral AgentsPhotosensitizing AgentsRadiation-Sensitizing AgentsSilver Compounds

Identifiers

PMID25543008
PMCPMC4433816
OpenAlexW2085199490

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.