Evidence map›Paper›PMID 25542911›Full record

Trial reportNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2015

E-Cigarettes and Smoking Cessation: Insights and Cautions From a Secondary Analysis of Data From a Study of Online Treatment-Seeking Smokers.

Jennifer L Pearson, Cassandra A Stanton, Sarah Cha, Raymond S Niaura, George Luta, Amanda L Graham

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01544153 (Improving Adherence to Web-Based Cessation Programs), which is not on this map. Cited by 41 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01544153 nacompletednot on this map

Improving Adherence to Web-Based Cessation Programs: A Social Network Approach

TypeinterventionalSponsorTruth InitiativeRan2012 to 2017Enrolled5,292ConditionsSmoking CessationArmsWEB, Social Network, Nicotine Replacement Therapy (NRT)
3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Overview of Electronic Nicotine Delivery Systems: A Systematic Review.American journal of preventive medicine · 2017
    Pooled it
  4. Pooled it
  5. Trial
  6. Article
  7. Article
  8. Applying the Population Health Standard to the Regulation of Electronic Nicotine Delivery Systems.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2021
    Review
  9. Article
  10. Trends in Attempts to Quit Smoking in England Since 2007: A Time Series Analysis of a Range of Population-Level Influences.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jennifer L PearsonSchroeder Institute for Tobacco Research and Policy Studies, Legacy, Washington, DC; Department of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD; jpearson@legacyforhealth.org.
Cassandra A StantonSchroeder Institute for Tobacco Research and Policy Studies, Legacy, Washington, DC; Department of Oncology, Georgetown University Medical Center/Cancer Prevention and Control Program, Lombardi Comprehensive Cancer Center, Washington, DC;
Sarah ChaSchroeder Institute for Tobacco Research and Policy Studies, Legacy, Washington, DC;
Raymond S NiauraSchroeder Institute for Tobacco Research and Policy Studies, Legacy, Washington, DC; Department of Oncology, Georgetown University Medical Center/Cancer Prevention and Control Program, Lombardi Comprehensive Cancer Center, Washington, DC;
George LutaDepartment of Oncology, Georgetown University Medical Center/Cancer Prevention and Control Program, Lombardi Comprehensive Cancer Center, Washington, DC; Department of Biostatistics, Bioinformatics, and Biomathematics, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC.
Amanda L GrahamSchroeder Institute for Tobacco Research and Policy Studies, Legacy, Washington, DC; Department of Oncology, Georgetown University Medical Center/Cancer Prevention and Control Program, Lombardi Comprehensive Cancer Center, Washington, DC;

Funding

Tissue Culture Shared ResourceP30CA051008 · NCI · GEORGETOWN UNIVERSITY · PI Habtom W Ressom · 1990 to 2026
$71.5M
Improving Adherence to Web-based Cessation Programs: A Social Network ApproachR01CA155489 · NCI · TRUTH INITIATIVE FOUNDATION · PI GRAHAM, AMANDA L · 2011 to 2015
$2.6M
EMA and Lab Assessment of Nicotine Dependence Among Dual End UsersK01DA037950 · NIDA · UNIVERSITY OF NEVADA RENO · PI PEARSON, JENNIFER LYNN · 2014 to 2017
$611k
NCI NIH HHS #5R01CA155489-03NCI NIH HHS P30 CA051008NCI NIH HHS P30CA051008NCI NIH HHS R01 CA155489NIDA NIH HHS #1K01DA037950-01NIDA NIH HHS K01 DA037950
6 · The paper itself

Abstract

backgroundEvidence from observational studies regarding the association between electronic cigarette (e-cigarette) use and cessation is mixed and difficult to interpret. Utilizing 2 analytic methods, this study illustrates challenges common in analyses of observational data, highlights measurement challenges, and reports associations between e-cigarette use and smoking cessation.

methodsData were drawn from an ongoing web-based smoking cessation trial. The sample was comprised of 2,123 participants with complete 3-month follow-up data. Logistic regression models with and without entropy balancing to control for confounds were conducted to evaluate the association between e-cigarette use and 30-day cigarette smoking abstinence.

resultsAt follow-up, 31.7% of participants reported using e-cigarettes to quit in the past 3 months. E-cigarette users differed from nonusers on baseline characteristics including cigarettes per day, Fagerström score, quit attempt in the past year, and previous use of e-cigarettes to quit. At follow-up, e-cigarette users made more quit attempts and employed more cessation aids than smokers who did not use e-cigarettes to quit. E-cigarette use was negatively associated with abstinence after adjustment for baseline characteristics; however, the association was not significant after additional adjustment for use of other cessation aids at 3 months.

conclusionsThe magnitude and significance of the estimated association between e-cigarette use and cessation in this study were dependent upon the analytical approach. Observational studies should employ multiple analytic approaches to address threats to validity. Future research should employ better measures of patterns of and reasons for e-cigarette use, frequency of e-cigarette use, and concurrent use of cessation aids.

Indexed as

Smoking PreventionAdultElectronic Nicotine Delivery SystemsFemaleFollow-Up StudiesHumansInternetLogistic ModelsMaleMiddle AgedPatient Acceptance of Health CareSmokingSmoking CessationUnited States

Identifiers

PMID25542911
PMCPMC4592337

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.