Evidence map›Paper›PMID 25542139›Full record

ArticleCancer causes & control : CCC2015

Maternal diet during pregnancy and unilateral retinoblastoma.

Christina Lombardi, Arupa Ganguly, Greta R Bunin, Saeedeh Azary, Vivian Alfonso, Beate Ritz, Julia E Heck

Open access · greenAbstract read
In one paragraph

Article in Cancer causes & control : CCC, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
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  11. Epidemiology and risk factors of retinoblastoma in Chongqing area.International journal of ophthalmology · 2016
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Christina LombardiDepartment of Epidemiology, UCLA Jonathan and Karin Fielding School of Public Health, 650 Charles E. Young Drive, Box 951772, Los Angeles, CA, 90095-1772, USA.
Arupa Ganguly
Greta R Bunin
Saeedeh Azary
Vivian Alfonso
Beate Ritz
Julia E Heck
Children's Hospital of Philadelphia · USUniversity of Pennsylvania · US

Funding

NCTN BIQSFP ANBL1531 (NRT)U10CA180886 · NCI · PUBLIC HEALTH INSTITUTE · PI Douglas S. Hawkins · 2014 to 2026
$390.6M
COG FOREIGN ACCRUALU10CA098543 · NCI · NATIONAL CHILDHOOD CANCER FOUNDATION · PI ADAMSON, PETER C. · 2003 to 2013
$335.5M
UCLA Career Development Program in Cancer Prevention and Control ResearchR25CA087949 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BASTANI, ROSHAN · 2000 to 2014
$6.8M
Parental genotypes and exposures in sporadic retinoblastomaR01CA118580 · NCI · UNIVERSITY OF PENNSYLVANIA · PI GANGULY, ARUPA · 2007 to 2011
$3.5M
Pesticide Exposure and Childhood Cancer StudyR21ES019986 · NIEHS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI RITZ, BEATE R. · 2011 to 2012
$409k
Parental Occupation and Childhood CancersR03ES021643 · NIEHS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HECK, JULIA · 2012 to 2013
$152k
NCI NIH HHS CA-118580-03S1NCI NIH HHS R01 CA118580NCI NIH HHS R01-CA118580NCI NIH HHS R25 CA087949NCI NIH HHS R25CA087949NCI NIH HHS U10 CA098543NCI NIH HHS U10 CA180886NIEHS NIH HHS R03 ES021643NIEHS NIH HHS R03ES021643NIEHS NIH HHS R21 ES019986NIEHS NIH HHS R21ES019986
6 · The paper itself

Abstract

purposePrevious studies have suggested a role for parental diet in childhood cancer prevention, but there are few studies of retinoblastoma. The aim of this study was to examine the relation between maternal diet and unilateral retinoblastoma.

methodsA case-control study of 163 unilateral RB cases and 136 controls ascertained information on maternal diet during pregnancy using a standardized food frequency questionnaire. Logistic regression was used to assess the relation between retinoblastoma and food groups and dietary patterns.

resultsWe observed a negative association between retinoblastoma and intake of fruit [odds ratio (OR) 0.38, 95 % confidence interval (CI) 0.14-1.02]. Positive associations were seen with intake of cured meats (OR 5.07, 95 % CI 1.63-15.70) and fried foods (OR 4.89, 95 % CI 1.72-13.89). A food pattern of high fruits and vegetables and low fried food and sweets was negatively associated with disease (OR 0.75, 95 % CI 0.61-0.92).

conclusionOur study provides preliminary evidence that mothers who consume diets higher in fruit and lower in fried foods and cured meats during pregnancy may reduce the risk of unilateral retinoblastoma in their offspring.

Indexed as

DietMaternal Nutritional Physiological PhenomenaAdolescentAdultCase-Control StudiesChildChild, PreschoolFeeding BehaviorFemaleFruitHumansInfantInfant, NewbornLogistic ModelsMaleMeat

Identifiers

PMID25542139
PMCPMC4334703
OpenAlexW1984428034

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.