ArticleCardiovascular engineering and technology2014
Characterization of regional deformation and material properties of the intact explanted vein by microCT and computational analysis.
Article in Cardiovascular engineering and technology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed, 4 citations in OpenAlex.
- An Image-Based Computational Framework to Evaluate the Material Stiffness of Arterial Tissue With High-Resolution Magnetic Resonance Imaging.Journal of biomechanical engineering · 2025Article
- A Pilot Experiment to Measure the Initial Mechanical Stability of the Femoral Head Implant in a Cadaveric Model of Osteonecrosis of Femoral Head Involving up to 50% of the Remaining Femoral Head.Medicina (Kaunas, Lithuania) · 2023Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
purposeDetailed mechanical information of the vein is important to better understand remodeling of the vessel in disease states, but has been difficult to obtain due to its thinness, unique geometry, and limitations of mechanical testing. This study presents a novel method for characterizing deformation of the intact explanted vein under physiological loads and determining its material properties by combining high-resolution imaging and computational analysis.
methodsHigh-resolution CT (microCT) was used to image an iodine-stained, excised porcine internal jugular vein sample under extension to 100% and 120% of
resultsThe observed morphology and regional strain of the vein were found to be relatively heterogeneous. The regional variability in the measured strain was primarily driven by geometry. Although iodine treatment may result in tissue stiffening, which requires additional investigation, it is effective in allowing detailed detection of vein geometry.
conclusionsThe feasibility and utility of using microCT and computational analysis to characterize mechanical responses and material properties of the vein were demonstrated. The presented method is a promising alternative or addition to mechanical testing for characterizing veins or other similarly delicate vessels in their native anatomical configuration under a wide range of realistic or simulated environmental and loading conditions.
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