ArticleFEBS letters2015
Uncapped 5' ends of mRNAs targeted by cytoplasmic capping map to the vicinity of downstream CAGE tags.
Article in FEBS letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- A transformer-based method for the cap analysis of gene expression and gene expression tag associated capping region prediction in RNA.RNA biology · 2026Article
- RNMT-dependent RNA cap methylation in health and disease.The Biochemical journal · 2025Review
- True length of diverse capped RNA sequencing (TLDR-seq): 5'-3'-end sequencing of capped RNAs regardless of 3'-end status.Nucleic acids research · 2025Article
- Widespread 3'UTR capped RNAs derive from G-rich regions in proximity to AGO2 binding sites.BMC biology · 2024Article
- Long noncoding RNAs are substrates for cytoplasmic capping enzyme.FEBS letters · 2023Article
- TERA-Seq: true end-to-end sequencing of native RNA molecules for transcriptome characterization.Nucleic acids research · 2021Article
- Cytoplasmic mRNA recapping has limited impact on proteome complexity.Open biology · 2020Article
- Analyzing (Re)Capping of mRNA Using Transcript Specific 5' End Sequencing.Bio-protocol · 2020Article
- AP-TSS: A New Method for the Analysis of RNA Expression from Particular and Challenging Transcription Start Sites.Biomolecules · 2020Article
- Inhibition of cytoplasmic cap methylation identifies 5' TOP mRNAs as recapping targets and reveals recapping sites downstream of native 5' ends.Nucleic acids research · 2020Article
- mRNA 5' ends targeted by cytoplasmic recapping cluster at CAGE tags and select transcripts are alternatively spliced.FEBS letters · 2019Article
- A recap of RNA recapping.Wiley interdisciplinary reviews. RNA · 2019Review
- RNA-binding proteins and heat-shock protein 90 are constituents of the cytoplasmic capping enzyme interactome.The Journal of biological chemistry · 2018Article
- RNA guanine-7 methyltransferase catalyzes the methylation of cytoplasmically recapped RNAs.Nucleic acids research · 2017Article
- African Swine Fever Virus NP868R Capping Enzyme Promotes Reovirus Rescue during Reverse Genetics by Promoting Reovirus Protein Expression, Virion Assembly, and RNA Incorporation into Infectious Virions.Journal of virology · 2017Article
- Regulation of mRNA capping in the cell cycle.RNA biology · 2017Review
- Putative RNA-directed adaptive mutations in cancer evolution.Transcription · 2016Article
- mRNA capping: biological functions and applications.Nucleic acids research · 2016Review
- Cap homeostasis is independent of poly(A) tail length.Nucleic acids research · 2016Article
- Identifying transcription start sites and active enhancer elements using BruUV-seq.Scientific reports · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
In mammalian transcriptomes approximately 25% of 5' ends determined by Capped Analysis of Gene Expression (CAGE) map to locations within spliced exons. The current study sought to determine if the cytoplasmic capping complex participates in generating these downstream CAGE tags. 5'-RACE was used to amplify the uncapped ends of target transcripts that accumulate when cytoplasmic capping is blocked. Sequencing of these RACE products mapped the positions of uncapped ends either exactly to or just downstream of archived CAGE tags. These findings support a role for cytoplasmic capping in generating the downstream capped ends identified by CAGE.
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Registered trials
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