ArticleInternational journal of ophthalmology2014
Uveitis associated with multiple sclerosis: complications and visual prognosis.
Article in International journal of ophthalmology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Pooled it
- CD11c+ CD8 T cells cause IFN-γ-dependent autoimmune neuroinflammation that is restrained by PD-1 signaling.JCI insight · 2026Article
- Ocular Manifestations of Multiple Sclerosis: A Retrospective, Population-Based Single-Center Study.Cureus · 2026Article
- Ophthalmic conditions in patients with multiple sclerosis.Multiple sclerosis and related disorders · 2025Article
- Juvenile Idiopathic Arthritis, Uveitis and Multiple Sclerosis: Description of Two Patients and Literature Review.Biomedicines · 2022Article
- The innate immune receptor Nlrp12 suppresses autoimmunity to the retina.Journal of neuroinflammation · 2022Article
- Uveitis prior to clinical presentation of Multiple Sclerosis (MS) is associated with better MS prognosis.PloS one · 2022Article
- Pediatric uveitis: Role of the pediatrician.Frontiers in pediatrics · 2022Review
- Review
- Incidence of uveitis and macular edema among patients taking fingolimod 0.5 mg for multiple sclerosis.Journal of ophthalmic inflammation and infection · 2020Article
- The Relationship Between Vasoproliferative Tumor and Uveitis in a Multiple Sclerosis Patient: A Case Report and Review of the LiteratureTurkish journal of ophthalmology · 2019Review
- Targeting CD6 for the treatment of experimental autoimmune uveitis.Journal of autoimmunity · 2018Article
- Granulomatous Panuveitis in Multiple Sclerosis: A Rare Occurrence.Annals of Indian Academy of NeurologyArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo determine the frequency, subtype, complications, treatment and visual prognosis of uveitis in patients with multiple sclerosis (MS).
methodsA total of 1702 MS patients' medical records were reviewed for a history of uveitis both with a neurologist and an ophthalmologist.
resultsNine patients (0.52%) with uveitis were detected. Eight of them were female, one was male. The mean age was 42.0±14.1y (range 22-66). Seven patients were relapsing remitting MS, two were secondary progressive MS. The mean duration of MS was 10.8±10.3y, and the mean duration of uveitis 10.3±9.9y. The onset of uveitis preceded that of MS (four patients) by a mean of 5.0±4.3y (range 1-11). MS diagnosed prior to the onset of uveitis (five patients) by an interval of 0.75-16y (mean 4.95±6.24y). There were 16 affected eyes of nine patients. The most common types of uveitis were panuveitis and intermediate uveitis. Uveitis was bilateral in most patients. The most common complications were cataract and glaucoma, and patients with such complications were surgically treated. The range of visual acuity of affected eyes was 20/800 to 20/22, with only six of 16 affected eyes better than 20/40. After treatment, the visual acuity of the affected eyes was better than 20/40 in 11 of 16 eyes.
conclusionUveitis should be considered when assessing an MS patient with visual loss, as surgical interventions other than medical treatments may be needed to improve visual function. Complications could be seen more often when posterior segment is involved.
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Registered trials
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