Evidence map›Paper›PMID 25540732›Full record

ReviewWorld journal of transplantation2014

Challenges in pediatric renal transplantation.

Licia Peruzzi, Alessandro Amore, Rosanna Coppo

Abstract readReview
In one paragraph

Review in World journal of transplantation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Licia PeruzziLicia Peruzzi, Alessandro Amore, Rosanna Coppo, University-Hospital Health Agency Città della Salute e della Scienza di Torino, Nephrology, Dialysis and Transplantation Unit, Regina Margherita University Children's Hospital, 10126 Turin, Italy.
Alessandro AmoreLicia Peruzzi, Alessandro Amore, Rosanna Coppo, University-Hospital Health Agency Città della Salute e della Scienza di Torino, Nephrology, Dialysis and Transplantation Unit, Regina Margherita University Children's Hospital, 10126 Turin, Italy.
Rosanna CoppoLicia Peruzzi, Alessandro Amore, Rosanna Coppo, University-Hospital Health Agency Città della Salute e della Scienza di Torino, Nephrology, Dialysis and Transplantation Unit, Regina Margherita University Children's Hospital, 10126 Turin, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transplantation in children is the best option to treat renal failure. Over the last 25 years the improvements in therapy have dramatically reduced the risk of early acute rejection and graft loss, however the long term results in terms of graft survival and morbidity still require search for new immunosuppressive regimens. Tolerance of the graft and minimization of side effects are the challenges for improving the outcome of children with a grafted kidney. Notwithstanding the difficulties in settling in children large multicenter trials to derive statistically useful data, many important contributions in the last years brought important modifications in the immunosuppressive therapy, including minimization protocols of steroids and calcineurin inhibitors and new induction drugs. New methods for diagnosis of anti HLA antibodies and some new protocols to improve both chance and outcome of transplantation in immunized subjects represent area of ongoing research of extreme interest for children.

Indexed as

Acute humoral rejectionChildrenDesensitizationImmunosuppressive therapyKidney transplantation

Identifiers

PMID25540732
PMCPMC4274593

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.