Evidence map›Paper›PMID 25540212›Full record

ArticleBMJ case reports2014

A woman's experience of tapering from buprenorphine during pregnancy.

Gabrielle Katrine Welle-Strand, Odd Kvamme, Andreas Andreassen, Edle Ravndal

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Gabrielle Katrine Welle-StrandNorwegian Centre for Addiction Research (Seraf), University of Oslo, Oslo, Norway Department of Psychiatry and Substance Use, Norwegian Directorate of Health, Oslo, Norway.
Odd KvammeLeirvik legekontor, Leirvik, Norway.
Andreas AndreassenDepartment of Pediatrics, Helse Fonna, Haugesund, Norway.
Edle RavndalNorwegian Centre for Addiction Research (Seraf), University of Oslo, Oslo, Norway.
Fonna Hospital TrustUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although opioid maintenance treatment (OMT) is the treatment of choice for pregnant opioid-dependent patients, some professionals argue that tapering the medication dose will reduce the severity of neonatal abstinence syndrome (NAS). This case description is based on the patient's detailed blog, and medical records from her general practitioner and the hospital. The patient is an employed, 32-year-old drug-abstinent woman in OMT. Her taper from 24 mg of buprenorphine started at 14 weeks' gestation and is slow, with withdrawal symptoms increasing gradually. In pregnancy week 31, she is off buprenorphine but she has severe withdrawal symptoms. She chose to go back on 4 mg of buprenorphine. The patient's son was born in pregnancy week 38+3, weighs 2950 g and does not require pharmacological treatment for NAS. The fetus most probably did experience fetal stress during the patient's tapering. It was the right decision by the patient to go back on buprenorphine.

Indexed as

Neonatal Abstinence SyndromeOpiate Substitution TreatmentPregnancy ComplicationsSubstance Withdrawal SyndromeAdultAnalgesics, OpioidBuprenorphineFemaleFetusGestational AgeHumansInfant, NewbornMaleNarcoticsParturitionPregnancyAnalgesics, OpioidBuprenorphineNarcotics

Identifiers

PMID25540212
PMCPMC4281552
OpenAlexW2053790698

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.