ArticleInternal and emergency medicine2015
Mortality at 30 and 90 days in elderly patients with pulmonary embolism: a retrospective cohort study.
Article in Internal and emergency medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Sex as a prognostic factor for mortality in adults with acute symptomatic pulmonary embolism.The Cochrane database of systematic reviews · 2025Pooled it
- Clinical outcomes of very elderly patients treated with ultrasound-assisted catheter-directed thrombolysis for pulmonary embolism: a systematic review.Journal of thrombosis and thrombolysis · 2021Pooled it
- Prognostic value of right ventricular dysfunction or elevated cardiac biomarkers in patients with low-risk pulmonary embolism: a systematic review and meta-analysis.European heart journal · 2019Pooled it
- Implementing an evidence-based computerized decision support system to improve patient care in a general hospital: the CODES study protocol for a randomized controlled trial.Implementation science : IS · 2016Trial
- Clinical characteristics and BGA-optimized pretest probability of pulmonary embolism in the elderly.Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2025Article
- Large-bore aspiration thrombectomy for the treatment of pulmonary embolism in octogenarians.CVIR endovascular · 2025Article
- Clinical characteristics and mortality predictors among very old patients with pulmonary thromboembolism: a multicenter study report.BMC pulmonary medicine · 2024Article
- The relation between thrombus burden and early mortality risk in inpatients diagnosed with COVID-19-related acute pulmonary embolism: a retrospective cohort study.BMC pulmonary medicine · 2023Article
- Endovenous radiofrequency ablation of great saphenous vein complicated by pulmonary embolism in an elderly patient.BMJ case reports · 2023Article
- EKOSJournal of clinical medicine · 2023Article
- Thrombolysis in Pulmonary Embolism: Octagenarians Deserve More Attention!Arquivos brasileiros de cardiologia · 2022Article
- Thrombolytic Therapy in Octogenarians with Acute Pulmonary Embolism.Arquivos brasileiros de cardiologia · 2022Article
- Safety and efficacy of catheter directed thrombolysis (CDT) in elderly with pulmonary embolism (PE).BMJ open respiratory research · 2021Observational
- Article
- Correlation of thrombosed vessel location and clot burden score with severity of disease and risk stratification in patients with acute pulmonary embolism.Anatolian journal of cardiology · 2020Article
- Predictors of medium- and long-term mortality in elderly patients with acute pulmonary embolism.Heliyon · 2020Article
- Health risk stratification based on computed tomography pulmonary artery obstruction index for acute pulmonary embolism.Scientific reports · 2018Article
- [Diagnosis and Treatment Strategy of Pulmonary Embolism after Video-assisted Thoracic Lobectomy].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2018Article
- Comorbidity assessment as predictor of short and long-term mortality in elderly patients with hemodynamically stable acute pulmonary embolism.Journal of thrombosis and thrombolysis · 2017Article
- Claims-based or clinical models for predicting 90-day post-pulmonary embolism outcomes.Internal and emergency medicine · 2017Article
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Authors and funding
13 authors.
Funding
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Abstract
Pulmonary Embolism (PE) incidence increases with age. Data on mortality and prognosis in elderly patients with suspected PE are lacking. (1) To assess 30- and 90-day mortality in subjects with PE from an elderly population seen in the emergency department (ED); (2) to test the prognostic accuracy of a simplified Pulmonary Embolism Severity Index (sPESI) coupled to a highly sensitive cardiac Troponin T (hs-cTnT) level. A retrospective cohort study was performed, including patients evaluated in the ED of Vimercate Hospital for clinically suspected PE from 2010 to 2012. Study population: n = 470, 63.4% women, mean age ± SD 73.06 ± 16.0 years, 40% aged ≥80 and 77.7% ≥65 years old, confirmed PE: 22.6% (106 cases). Within 30 and 90 days, mortality among patients with confirmed PE was 14.2% (8.8-22.0) and 20.8% (16.5-41.7). In subjects aged ≥80 years, 30-day mortality was 18.9% among patients with confirmed PE, and 12.6% among those with PE excluded (p = 0.317). Ninety-day mortality rates were 29.7 and 19.9%, respectively (p = 0.193). In patients with confirmed PE, Negative Predictive Value of sPESI was 94.1% (80.3-99.3) for 30 days and 88.2% (72.3-96.7) for 90-day mortality. Adding the hs-cTnT level to sPESI did not improve its performance. (1) In an elderly population referring to the ED with clinically suspected PE, mortality was high both in subjects with and without confirmed PE; (2) the ability of sPESI and hs-cTnT to predict PE mortality seems to be lower than reported in studies based on data from younger populations. Better risk stratification tools will be necessary to improve clinical management in this setting.
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