Evidence map›Paper›PMID 25539823›Full record

Trial reportItalian journal of pediatrics2014

SETIL: Italian multicentric epidemiological case-control study on risk factors for childhood leukaemia, non hodgkin lymphoma and neuroblastoma: study population and prevalence of risk factors in Italy.

Corrado Magnani, Stefano Mattioli, Lucia Miligi, Alessandra Ranucci, Roberto Rondelli, Alberto Salvan, Luigi Bisanti, Giuseppe Masera, Carmelo Rizzari, Paola Zambon and 28 more

Open access · goldAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Italian journal of pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Air Pollution and Health: The Need for a Medical Reading of Environmental Monitoring Data.International journal of environmental research and public health · 2020
    Article
  4. Article
  5. Review
  6. Article
  7. Childhood leukemia and 50 Hz magnetic fields: findings from the Italian SETIL case-control study.International journal of environmental research and public health · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors at 20 institutions in 1 country.

Corrado Magnani
Stefano Mattioli
Lucia Miligi
Alessandra Ranucci
Roberto Rondelli
Alberto Salvan
Luigi Bisanti
Giuseppe Masera
Carmelo Rizzari
Paola Zambon
Santina Cannizzaro
Lorenzo Gafà
Lia Lidia Luzzatto
Alessandra Benvenuti
Paola Michelozzi
Ursula Kirchmayer
Pierluigi Cocco
Pierfranco Biddau
Claudia Galassi
Egidio Celentano
Erni Guarino
Giorgio Assennato
Gigliola de Nichilo
Domenico Franco Merlo
Vittorio Bocchini
Franco Pannelli
Paola Mosciatti
Liliana Minelli
Manuela Chiavarini
Marina Cuttini
Veronica Casotto
Maria Valeria Torregrossa
Rosalia Maria Valenti
Francesco Forastiere
Riccardo Haupt
Susanna Lagorio
Serena Risica
Alessandro Polichetti
Piedmont Reference Center for Epidemiology and Cancer Prevention · ITLega Italiana per la Lotta ai Tumori · ITOspedale Policlinico San Martino · ITRegione Campania · ITRegione LazioUniversità di Camerino · ITUniversity of Palermo · ITUniversity of Perugia · ITAzienda Ospedaliera San Gerardo · ITBambino Gesù Children's Hospital · ITIRCCS Materno Infantile Burlo Garofolo · ITIstituto di Analisi dei Sistemi ed Informatica Antonio Ruberti · ITIstituto Giannina Gaslini · ITOspedale Microcitemico · ITPoliclinico S.Orsola-Malpighi · ITRegione Puglia · ITTorino e-district · ITUniversity of Bologna · ITUniversity of Cagliari · ITUniversity of Milano-Bicocca · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAetiology of childhood leukaemia and childhood neoplasm is poorly understood. Information on the prevalence of risk factors in the childhood population is limited. SETIL is a population based case-control study on childhood leukaemia, conducted with two companion studies on non-Hodgkin Lymphoma (NHL) and neuroblastoma. The study relies on questionnaire interviews and 50 Hz magnetic field (ELF-MF) indoor measurements. This paper discusses the SETIL study design and includes descriptive information.

methodsThe study was carried out in 14 Italian regions (78.3% of Italian population aged 0-10). It included leukaemia, NHL and neuroblastoma cases incident in 0-10 year olds in 1998-2001, registered by the Italian Association of Paediatric Haematology and Oncology (AIEOP) (accrual over 95% of estimated incidence). Two controls for each leukaemia case were randomly sampled from the Local Health Authorities rolls, matched by gender, birthdate and residence. The same controls were used in NHL and neuroblastoma studies. Parents were interviewed at home on: physical agents (ELF-MF and ionizing radiation), chemicals (smoking, solvents, traffic, insecticides), occupation, medical and personal history of children and parents, infectious diseases, immunizations and associated factors. Occupational exposure was collected using job specific modules. ELF-MF was measured in the main rooms (spot measurement) and close to child's bed (48 hours measurement).

resultsThe study included: 683 leukaemia cases (87% ALL, 13% AnLL), 97 NHL, 155 neuroblastomas, and 1044 controls.

conclusionsSETIL represents a data source on exposure of Italian children to a broad array of potential carcinogenic factors.

Indexed as

ChildChild, PreschoolEnvironmental ExposureFemaleHumansIncidenceInfantInfant, NewbornItalyLymphoma, Non-HodgkinMaleNeuroblastomaPrevalenceRisk AssessmentRisk Factors

Identifiers

PMID25539823
PMCPMC4310183
OpenAlexW2166308831

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.