Evidence map›Paper›PMID 25539658›Full record

Trial reportBMC psychiatry2014

Validity of subjective versus objective quality of life assessment in people with schizophrenia.

Karen P Hayhurst, Jennifer A Massie, Graham Dunn, Shôn W Lewis, Richard J Drake

Open access · goldAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in BMC psychiatry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 59 citations in OpenAlex.

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  12. Mastication, swallowing, and salivary flow in patients with head and neck cancer: objective tests versus patient-reported outcomes.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
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  13. Quality of Life of People with Severe Mental Health Problems: Testing an Interactive Model.International journal of environmental research and public health · 2020
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  15. The effects of clinical illness severity and physical activity on health-related quality of life in schizophrenia.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019
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  17. Subjectively different but objectively the same? Three profiles of QoL in people with severe mental health problems.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Karen P HayhurstInstitute of Brain, Behaviour and Mental Health, The University of Manchester, Manchester, M13 9PL, UK. karen.hayhurst@manchester.ac.uk.
Jennifer A MassieLaureate House Mental Health Unit, Manchester Mental Health & Social Care Trust, Wythenshawe Hospital, Southmoor Road, Manchester, UK. Jenny.Massie@mhsc.nhs.uk.
Graham DunnCentre for Biostatistics, Institute of Population Health, The University of Manchester, Manchester, UK. graham.dunn@manchester.ac.uk.
Shôn W LewisInstitute of Brain, Behaviour and Mental Health, The University of Manchester, Manchester, M13 9PL, UK. shon.lewis@manchester.ac.uk.
Richard J DrakeInstitute of Brain, Behaviour and Mental Health, The University of Manchester, Manchester, M13 9PL, UK. richard.drake@manchester.ac.uk.
University of Manchester · GBManchester Academic Health Science Centre · GBWythenshawe Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundQuality of life (QoL) is considered an important outcome in health research. It can be rated by the patient, or by an external assessor. We wished to identify the predictors of any discrepancies between these two approaches in people with schizophrenia.

methodsPatients with DSM schizophrenia and related disorders (N = 80) completed both patient-rated (Lancashire Quality of Life Profile; LQOLP) and assessor-rated (Heinrich's Quality of Life Scale; QLS) measures of QoL.

resultsPatient-rated (LQOLP) and assessor-rated (QLS) measures showed a modest correlation (r = 0.38). In a regression analysis, independent predictors of subjectively-rated QoL being higher than objectively-assessed QoL in the same patient, were low insight score (BIS), negative symptoms (PANSS), absence of depression (CDSS), and less positive attitude toward prescribed treatment (DAI).

conclusionsIn people with schizophrenia, scores on objectively- and subjectively-rated measures of quality of life can differ markedly. When comparing subjective to objective assessments, patients with depressive symptoms will value their QoL lower, and those with low insight will value their QoL higher. This has important implications for the utility and interpretation of QoL measures in schizophrenia.

Indexed as

Quality of LifeSchizophrenic PsychologyAdolescentAdultAgedAntipsychotic AgentsDepressive DisorderDrug SubstitutionFemaleHumansMaleMiddle AgedPatient SatisfactionPsychotic DisordersSchizophreniaSchizophrenia, ParanoidAntipsychotic Agents

Identifiers

PMID25539658
PMCPMC4300039
OpenAlexW2144676612

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.