Evidence map›Paper›PMID 25538901›Full record

ArticleEuropean thyroid journal2014

Environmental, lifestyle, and anthropometric risk factors for differentiated thyroid cancer in cuba: a case-control study.

Juan J Lence-Anta, Constance Xhaard, Rosa M Ortiz, Haoiinda Kassim, Celia M Pereda, Silvia Turcios, Milagros Velasco, Mae Chappe, Idalmis Infante, Marlene Bustillo and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in European thyroid journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 4 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 4 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Time for Re-Evaluating the Human Carcinogenicity of Ethylenedithiocarbamate Fungicides? A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
  2. Effect of Cigarette Smoking on Thyroid Cancer: Meta-Analysis.Endocrinology and metabolism (Seoul, Korea) · 2021
    Pooled it
  3. Pooled it
  4. Pooled it
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  7. GA Genotype of the Arg280His Polymorphism on TheBalkan journal of medical genetics : BJMG · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Juan J Lence-AntaInstitute of Oncology and Radiobiology, Havana, Cuba.
Constance XhaardRadiation Epidemiology Group, 1018 INSERM Unit, Villejuif, France ; Institut Gustave Roussy, Villejuif, France ; University Paris-Sud, Villejuif, France.
Rosa M OrtizInstitute of Oncology and Radiobiology, Havana, Cuba.
Haoiinda KassimRadiation Epidemiology Group, 1018 INSERM Unit, Villejuif, France ; Institut Gustave Roussy, Villejuif, France ; University Paris-Sud, Villejuif, France.
Celia M PeredaInstitute of Oncology and Radiobiology, Havana, Cuba.
Silvia TurciosNational Institute of Endocrinology, Havana, Cuba.
Milagros VelascoInstitute of Oncology and Radiobiology, Havana, Cuba.
Mae ChappeInstitute of Oncology and Radiobiology, Havana, Cuba.
Idalmis InfanteInstitute of Oncology and Radiobiology, Havana, Cuba.
Marlene BustilloInstitute of Oncology and Radiobiology, Havana, Cuba.
Anabel GarcíaInstitute of Oncology and Radiobiology, Havana, Cuba.
Enora CleroRadiation Epidemiology Group, 1018 INSERM Unit, Villejuif, France ; Institut Gustave Roussy, Villejuif, France ; University Paris-Sud, Villejuif, France.
Stephane MaillardRadiation Epidemiology Group, 1018 INSERM Unit, Villejuif, France ; Institut Gustave Roussy, Villejuif, France ; University Paris-Sud, Villejuif, France.
Sirced SalazarInstitute of Oncology and Radiobiology, Havana, Cuba.
Regla RodriguezCuban Health Public Ministry, Havana, Cuba.
Florent de VathaireRadiation Epidemiology Group, 1018 INSERM Unit, Villejuif, France ; Institut Gustave Roussy, Villejuif, France ; University Paris-Sud, Villejuif, France.
Instituto de Oncología y Radiobiología · CUMinisterio de Salud Pública · CU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence of differentiated thyroid carcinoma (DTC) is low in people of African origin and higher in populations living on islands, but there is no well-established explanation for these differences. Cuba is a multiethnic nation with people of African and Spanish descent. Until now, no study on the risk factors of DTC has focused on the Cuban population. Our aim is to establish the role of environmental and lifestyle factors and to relate anthropometric measurements to the risk of developing DTC in Cuba.

methodsWe performed a case-control study of 203 DTC patients treated in two hospitals in Havana and 212 controls living in the area covered by these hospitals (i.e. parts of Havana and the municipality of Jaruco). Risk factors were analyzed using conditional logistic regression.

resultsAs has been shown by other studies, we found that non-African ethnicity, never smoking, parity, and high body mass index are risk factors significantly associated with DTC, whereas a history of exposure to ionizing radiation and level of education were not significantly related with disease development. Being rhesus factor-positive, having a personal history of benign thyroid disorder, agricultural occupation, and consumption of artesian well water were also associated with a significantly increased risk of developing DTC.

conclusionsThe original findings reported here concern the risk of DTC that was associated with non-African ethnicity, positive rhesus factor, farming, and drinking water from an artesian well.

Indexed as

Case-control studyCubaDifferentiated thyroid cancerEpidemiologyRisk factors

Identifiers

PMID25538901
PMCPMC4224259
OpenAlexW2050072444

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.