Evidence map›Paper›PMID 25538837›Full record

ArticleInternational journal of preventive medicine2014

Cardiovascular Risk Factors and Nutritional Intake are not Associated with Ultrasound-defined Increased Carotid Intima Media Thickness in Individuals Without a History of Cardiovascular Events.

Mahmoud Reza Azarpazhooh, Seyyed Mohammad Reza Kazemi-Bajestani, Habib Esmaeili, Payam Vedadian, Mahmoud Ebrahimi, Seyyed Mohammad Reza Parizadeh, Ali Reza Heidari-Bakavoli, Mohsen Moohebati, Mohammad Safarian, Naghmeh Mokhber and 4 more

Open access · greenAbstract read
In one paragraph

Article in International journal of preventive medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Carotid Intima-Media Thickness in Indonesian Subjects with Cardiovascular Disease Risk Factors Who Were Not Receiving Lipid-Lowering Agents.The International journal of angiology : official publication of the International College of Angiology, Inc · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Mahmoud Reza AzarpazhoohBiochemistry and Nutrition Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Seyyed Mohammad Reza Kazemi-BajestaniCardiovascular Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Habib EsmaeiliDepartment of Statistics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Payam VedadianBiochemistry and Nutrition Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mahmoud EbrahimiCardiovascular Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Seyyed Mohammad Reza ParizadehBiochemistry and Nutrition Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Ali Reza Heidari-BakavoliCardiovascular Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohsen MoohebatiCardiovascular Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohammad SafarianBiochemistry and Nutrition Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Naghmeh MokhberPsychiatry and Behavioral Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohsen NematyBiochemistry and Nutrition Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohsen MazidiBiochemistry and Nutrition Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Gorden A FernsDivision of Medical Education, Brighton and Sussex Medical School, RM 342, Mayfield House, University of Brighton, BN1 9PH, UK.
Majid Ghayour-MehrabaniBiochemistry and Nutrition Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran ; Cardiovascular Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mashhad University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCarotid ultrasound appears to be useful in the assessment of cardiovascular risk. In this study, we have assessed the carotid intima-media thickness (CIMT) in a group of individuals without a history of cardiovascular events.

methodsA sample of 431subjects (189 [43.9%] males and 242 [56.1%] females) was obtained from an urban population using a stratified-cluster method in Mashhad stroke and heart atherosclerosis disorder study. None of the subjects had a history of the cardiovascular event. Carotid artery duplex ultrasound was used to determine the CIMT in all subjects, and to identify those with an abnormal value (CIMT [+]; i.e., CIMT ≥ 0.8 mm). Dietary intake of participants was assessed using a questionnaire for 24-h dietary recall. The relationship between anthropometric, biochemical and dietary data and CIMT were assessed.

resultsThe mean age of subjects was 48.7 ± 8.0 years. Of the 431 patients, 118 (27.4%) were found to be CIMT (+). Of the cardiovascular parameters assessed, only age (odds ratio [OR] [95% confidence interval (CI)], 1.11 [0.56-4.34]; P < 0.01) and male gender (OR [95% CI], 1.14 [0.63-2.23]; P < 0.05) were significant independent predictors of ultrasound defined CIMT. Crude and total energy adjusted intake were not associated with the presence of CIMT (+).

conclusionsIt appears that within a relatively young Iranian population of individuals without a history of cardiovascular event, the presence of CIMT (+) defined by duplex ultrasound cut-off value of ≥0.8 mm, did not associate with several modifiable cardiovascular risk factors or measures of dietary intake.

Indexed as

Carotid artery atherosclerosisduplex ultrasoundintima-media thicknessnutritional intakerisk factors

Identifiers

PMID25538837
PMCPMC4274548
OpenAlexW2134572880

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.