ArticleFrontiers in microbiology2014
Nucleotide sequence of conjugative prophage Φ1207.3 (formerly Tn1207.3) carrying the mef(A)/msr(D) genes for efflux resistance to macrolides in Streptococcus pyogenes.
Article in Frontiers in microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 46 citations in OpenAlex.
- Eco-evolutionary feedbacks drive the co-occurrence of restriction-modification systems and antimicrobial resistance genes in bacteria.PLoS biology · 2026Article
- Increase of macrolide resistance amongAntimicrobial agents and chemotherapy · 2025Article
- Global spread of Streptococcus pyogenes A genomics-supported narrative review.FEMS microbiology reviews · 2025Review
- Overlapping Streptococcus pyogenes and Streptococcus dysgalactiae subspecies equisimilis household transmission and mobile genetic element exchange.Nature communications · 2024Article
- A novel invasive Streptococcus pyogenes variant sublineage derived through recombinational replacement of the emm12 genomic region.Scientific reports · 2023Article
- The mobilome ofMicrobial genomics · 2023Article
- TheJournal of bacteriology · 2023Article
- Regulation of the macrolide resistance ABC-F translation factor MsrD.Nature communications · 2023Article
- The Mobilome-Enriched Genome of the Competence-DeficientMicroorganisms · 2023Article
- The persistence and stabilization of auxiliary genes in the human skin virome.Virology journal · 2023Article
- Streptococcus pyogenes Φ1207.3 Is a Temperate Bacteriophage Carrying the Macrolide Resistance Gene PairMicrobiology spectrum · 2023Article
- The culmination of multidrug-resistant efflux pumps vs. meager antibiotic arsenal era: Urgent need for an improved new generation of EPIs.Frontiers in microbiology · 2023Review
- Article
- Global diversity and distribution of prophages are lineage-specific within the Ralstonia solanacearum species complex.BMC genomics · 2022Article
- How GBS Got Its Hump: Genomic Analysis of Group BPathogens (Basel, Switzerland) · 2022Article
- Bacterial Multidrug Efflux Pumps at the Frontline of Antimicrobial Resistance: An Overview.Antibiotics (Basel, Switzerland) · 2022Review
- Predicted transmembrane proteins with homology to Mef(A) are not responsible for complementing mef(A) deletion in the mef(A)-msr(D) macrolide efflux system in Streptococcus pneumoniae.BMC research notes · 2021Article
- A Mating Procedure for Genetic Transfer of Integrative and Conjugative Elements (ICEs) of Streptococci and Enterococci.Methods and protocols · 2021Article
- High copy number and highly stable Escherichia coli-Bacillus subtilis shuttle plasmids based on pWB980.Microbial cell factories · 2020Article
- Characterization of Bacteriophage Peptides of PathogenicFrontiers in microbiology · 2020Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Genetic element Φ1207.3 (formerly Tn1207.3) is a prophage of Streptococcus pyogenes which carries the macrolide efflux resistance genes mef(A)/msr(D) and is capable of conjugal transfer among streptococci. Complete nucleotide sequence showed that Φ1207.3 is 52,491 bp in length and contained 58 open reading frames (ORFs). A manual homology-based annotation with functional prediction of the hypothetical gene product was possible only for 34 out of 58 ORFs. Φ1207.3 codes for two different C-methylation systems, several phage structural genes, a lysis cassette (composed by a holin and a peptidoglycan hydrolase), and three site-specific resolvases of the serine recombinase family.
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