Evidence map›Paper›PMID 25538578›Full record

ArticleFrontiers in behavioral neuroscience2014

Virtual multiple errands test (VMET): a virtual reality-based tool to detect early executive functions deficit in Parkinson's disease.

Pietro Cipresso, Giovanni Albani, Silvia Serino, Elisa Pedroli, Federica Pallavicini, Alessandro Mauro, Giuseppe Riva

Open access · goldAbstract read
In one paragraph

Article in Frontiers in behavioral neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 96 citations in OpenAlex.

  1. Pooled it
  2. The role of virtual reality on outcomes in rehabilitation of Parkinson's disease: meta-analysis and systematic review in 1031 participants.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020
    Pooled it
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  12. The night out task and scoring application: an ill-structured, open-ended clinic-based test representing cognitive capacities used in everyday situations.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2021
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  19. Lesion Studies in Contemporary Neuroscience.Trends in cognitive sciences · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Pietro CipressoApplied Technology for Neuro-Psychology Lab, IRCCS Istituto Auxologico Italiano Milano, Italy.
Giovanni AlbaniDivision of Neurology and Neurorehabilitation, IRCCS Istituto Auxologico Italiano Oggebbio, Italy.
Silvia SerinoApplied Technology for Neuro-Psychology Lab, IRCCS Istituto Auxologico Italiano Milano, Italy.
Elisa PedroliApplied Technology for Neuro-Psychology Lab, IRCCS Istituto Auxologico Italiano Milano, Italy.
Federica PallaviciniApplied Technology for Neuro-Psychology Lab, IRCCS Istituto Auxologico Italiano Milano, Italy.
Alessandro MauroDivision of Neurology and Neurorehabilitation, IRCCS Istituto Auxologico Italiano Oggebbio, Italy.
Giuseppe RivaApplied Technology for Neuro-Psychology Lab, IRCCS Istituto Auxologico Italiano Milano, Italy ; Department of Psychology, Università Cattolica del Sacro Cuore Milano, Italy.
IRCCS Istituto Auxologico Italiano · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSeveral recent studies have pointed out that early impairment of executive functions (EFs) in Parkinson's Disease (PD) may be a crucial marker to detect patients at risk for developing dementia. The main objective of this study was to compare the performances of PD patients with mild cognitive impairment (PD-MCI) with PD patients with normal cognition (PD-NC) and a control group (CG) using a traditional assessment of EFs and the Virtual Multiple Errands Test (VMET), a virtual reality (VR)-based tool. In order to understand which subcomponents of EFs are early impaired, this experimental study aimed to investigate specifically which instrument best discriminates among these three groups. MATERIALS AND

methodsThe study included three groups of 15 individuals each (for a total of 45 participants): 15 PD-NC; 15 PD-MCI, and 15 cognitively healthy individuals (CG). To assess the global neuropsychological functioning and the EFs, several tests (including the Mini Mental State Examination (MMSE), Clock Drawing Test, and Tower of London test) were administered to the participants. The VMET was used for a more ecologically valid neuropsychological evaluation of EFs.

resultsFindings revealed significant differences in the VMET scores between the PD-NC patients vs. the controls. In particular, patients made more errors in the tasks of the VMET, and showed a poorer ability to use effective strategies to complete the tasks. This VMET result seems to be more sensitive in the early detection of executive deficits because these two groups did not differ in the traditional assessment of EFs (neuropsychological battery).

conclusionThis study offers initial evidence that a more ecologically valid evaluation of EFs is more likely to lead to detection of subtle executive deficits.

Indexed as

executive functionmild cognitive impairmentParkinson’s diseasepsychometric assessmentvirtual realityVMET

Identifiers

PMID25538578
PMCPMC4257151
OpenAlexW2026406559

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.