Evidence map›Paper›PMID 25538527›Full record

ArticleSaudi journal of anaesthesia2014

Effect of dexmedetomidine as adjuvant in ropivacaine-induced supraclavicular brachial plexus block: A prospective, double-blinded and randomized controlled study.

Anjan Das, Saikat Majumdar, Susanta Halder, Surajit Chattopadhyay, Saswati Pal, Ratul Kundu, Subrata Kumar Mandal, Sandip Chattopadhyay

Retracted Registry-linked trialOpen access · diamondAbstract readRetracted Publication
In one paragraph

Article in Saudi journal of anaesthesia, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. It is linked to trial NCT02787018 (Dexamethasone Compared With Dexmedetomidine as an Adjuvant to Ropivacaine for Supraclavicular Brachial Plexus Block), which is not on this map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02787018 phase3completednot on this mapstarted 2016, after this paper: background citation

Dexamethasone Compared With Dexmedetomidine as an Adjuvant to Ropivacaine for Supraclavicular Brachial Plexus Block

TypeinterventionalSponsorB.P. Koirala Institute of Health SciencesRan2016 to 2018Enrolled120ConditionsBrachial Plexus BlockArmsRopivacaine and Normal saline, Ropivacaine and Dexamethasone, Ropivacaine and Dexmedetomidine
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 67 citations in OpenAlex.

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  18. Retraction.Saudi journal of anaesthesia
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4 · The record

Corrections and comments

  • Retraction · 2020-05-30Falsification/Fabrication of Data · Investigation by Journal/Publisher · Objections by Third Party · Plagiarism of/in Article ·
  • Retracted
5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Anjan DasDepartment of Anaesthesiology, College of Medicine & Sagore Dutta Hospital, Kolkata, West Bengal, India.
Saikat MajumdarDepartment of Anaesthesiology, NRS Medical College, Kolkata, West Bengal, India.
Susanta HalderDepartment of Anaesthesiology, R. G. Kar Medical College, Kolkata, West Bengal, India.
Surajit ChattopadhyayDepartment of Anaesthesiology, Bankura Sammilani Medical College, Bankura, West Bengal, India.
Saswati PalDepartment of Anaesthesiology, NRS Medical College, Kolkata, West Bengal, India.
Ratul KunduDepartment of Anaesthesiology, Institute of Post Graduate Medical Education And Research, Kolkata, West Bengal, India.
Subrata Kumar MandalDepartment of Anaesthesiology, College of Medicine & Sagore Dutta Hospital, Kolkata, West Bengal, India.
Sandip ChattopadhyayDepartment of G & O, College of Medicine & Sagore Dutta Hospital, Kolkata, West Bengal, India.
Bankura Sammilani Medical College · INCollege of Medicine & Sagore Dutta Hospital · INMedical College and Hospital, Kolkata · INInstitute of Post Graduate Medical Education and Research · INR. G. Kar Medical College and Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsDifferent additives have been used to prolong brachial plexus block. We evaluated the effect of adding dexmedetomidine to ropivacaine for supraclavicular brachial plexus blockade. The primary endpoints were the onset and duration of sensory and motor block and duration of analgesia. MATERIALS AND

methodsA total of 84 patients (20-50 years) posted for elective forearm and hand surgery under supraclavicular brachial plexus block were divided into two equal groups (Group R and RD) in a randomized, double-blind fashion. In group RD (n = 42) 30 ml 0.5% ropivacaine +1 ml (100 μg) of dexmedetomidine and group R (n = 42) 30 ml 0.5% ropivacaine +1 ml normal saline were administered in supraclavicular block. Sensory and motor block onset times and block durations, time to first analgesic use, total analgesic need, postoperative visual analog scale (VAS), hemodynamics and side-effects were recorded for each patient.

resultsThough with similar demographic profile in both groups, sensory and motor block in group RD (P < 0.05) was earlier than group R. Sensory and motor block duration and time to first analgesic use were significantly longer and the total need for rescue analgesics was lower in group RD (P < 0.05) than group R. Post-operative VAS value at 12 h were significantly lower in group RD (P < 0.05). Intra-operative hemodynamics were significantly lower in group RD (P < 0.05) without any appreciable side-effects.

conclusionIt can be concluded that adding dexmedetomidine to supraclavicular brachial plexus block increases the sensory and motor block duration and time to first analgesic use, and decreases total analgesic use with no side-effects.

Indexed as

Dexmedetomidineropivacainesupraclavicular brachial plexus block

Identifiers

PMID25538527
PMCPMC4268534
OpenAlexW2005787472

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.