Evidence map›Paper›PMID 25538378›Full record

ArticleMediators of inflammation2014

Prognostic value of plasma pentraxin-3 levels in patients with stable coronary artery disease after drug-eluting stent implantation.

Liu Haibo, Guo Xiaofang, Wang Chunming, Yuan Jie, Chen Guozhong, Zhang Limei, Cao Yong, Fang Yu, Bao Yingchun, Yu Wangjun and 1 more

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Pentraxin 3 in Cardiovascular Disease.Frontiers in immunology · 2019
    Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Liu HaiboShanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai 200032, China ; Department of Cardiology, Yinzhou People's Hospital Affiliated to Medical School of Ningbo University, Ningbo 315040, China.
Guo XiaofangClinical Laboratory Center, Yinzhou People's Hospital Affiliated to Medical School of Ningbo University, Ningbo 315040, China.
Wang ChunmingDepartment of Cardiology, Yinzhou People's Hospital Affiliated to Medical School of Ningbo University, Ningbo 315040, China.
Yuan JieShanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Chen GuozhongDepartment of Cardiology, Yinzhou People's Hospital Affiliated to Medical School of Ningbo University, Ningbo 315040, China.
Zhang LimeiDepartment of Cardiology, Yinzhou People's Hospital Affiliated to Medical School of Ningbo University, Ningbo 315040, China.
Cao YongDepartment of Cardiology, Yinzhou People's Hospital Affiliated to Medical School of Ningbo University, Ningbo 315040, China.
Fang YuDepartment of Cardiology, Yinzhou People's Hospital Affiliated to Medical School of Ningbo University, Ningbo 315040, China.
Bao YingchunDepartment of Cardiology, Yinzhou People's Hospital Affiliated to Medical School of Ningbo University, Ningbo 315040, China.
Yu WangjunClinical Laboratory Center, Yinzhou People's Hospital Affiliated to Medical School of Ningbo University, Ningbo 315040, China.
Ge JunboShanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Ningbo University · CNFudan University · CNSun Yat-sen University · CNThe First Affiliated Hospital, Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pentraxin-3 (PTX3) is an inflammatory marker thought to be more specific to cardiovascular inflammation than C-reactive protein (CRP). Our aim was to assess the prognostic value of PTX3 in patients with stable coronary artery disease (CAD) after drug eluting stent (DES) implantation. Plasma PTX3 levels were measured before percutaneous coronary intervention (PCI) and at 24 h post-PCI in 596 consecutive patients with stable CAD. Patients were followed up for a median of 3 years (range 1-5) for major adverse cardiovascular events (MACEs). We found that the post-PCI plasma PTX3 levels were significantly higher at 24 h after PCI than pre-PCI, patients with MACEs had higher post-PCI PTX3 levels compared with MACEs-free patients, patients with higher post-PCI PTX3 levels (median > 4.384 ng/mL) had a higher risk for MACEs than those with PTX3 < 4.384 ng/mL, and post-PCI PTX3, cTnI, multiple stents, and age but not high-sensitivity CRP (hsCRP) were independently associated with the prevalence of MACEs after DES implantation. The present study shows that post-PCI PTX3 may be a more reliable inflammatory predictor of long-term MACEs in patients with stable CAD undergoing DES implantation than CRP. Measurement of post-PCI PTX3 levels could provide a rationale for risk stratification of patients with stable CAD after DES implantation.

Indexed as

Drug-Eluting StentsAgedCoronary Artery DiseaseC-Reactive ProteinFemaleFollow-Up StudiesHumansInflammationKaplan-Meier EstimateMaleMiddle AgedMultivariate AnalysisPaclitaxelPentraxinsPercutaneous Coronary InterventionPrognosisC-Reactive ProteinPaclitaxelPentraxinsSerum Amyloid P-ComponentSirolimuszotarolimus

Identifiers

PMID25538378
PMCPMC4265374
OpenAlexW2157618013

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.