Evidence map›Paper›PMID 25538279›Full record

ArticleDiabetes2015

Mineralocorticoid receptors: an appealing target to treat coronary microvascular dysfunction in diabetes.

Shawn B Bender, Guanghong Jia, James R Sowers

Abstract readComment
In one paragraph

Article in Diabetes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Coronary microvascular dysfunction in diabetes mellitus.The Journal of international medical research · 2017
    Review
  3. Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Shawn B BenderResearch, Harry S. Truman Memorial Veterans Hospital, Columbia, MO Department of Biomedical Sciences, University of Missouri, Columbia, MO Dalton Cardiovascular Research Center, University of Missouri, Columbia, MO.
Guanghong JiaResearch, Harry S. Truman Memorial Veterans Hospital, Columbia, MO Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, University of Missouri School of Medicine, Columbia, MO.
James R SowersResearch, Harry S. Truman Memorial Veterans Hospital, Columbia, MO Dalton Cardiovascular Research Center, University of Missouri, Columbia, MO Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, University of Missouri School of Medicine, Columbia, MO Department of Medical Pharmacology and Physiology, University of Missouri School of Medicine, Columbia, MO sowersj@health.missouri.edu.

Funding

ANG II OPPOSES INS MEDIATED VASORELAXATION &GLU UTILZAR01HL073101 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI SOWERS, JAMES RUSSELL · 2004 to 2013
$2.7M
Ang II and Overnutrition and Insulin resistance in Cardiovascular TissueR01HL107910 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI SOWERS, JAMES RUSSELL · 2011 to 2015
$1.8M
Interactions of the RAAS and a Western Diet on Insulin Metabolic ActionsI01BX001981 · VA · HARRY S. TRUMAN MEMORIAL VA HOSPITAL · PI LASTRA, GUIDO · 2013 to 2022
–
Mineralocorticoid Receptor-Mediated Vascular Insulin ResistanceIK2BX002030 · VA · HARRY S. TRUMAN MEMORIAL VA HOSPITAL · PI BENDER, SHAWN BRADY · 2013 to 2017
–
BLRD VA I01 BX001981BLRD VA IK2 BX002030NHLBI NIH HHS R01 HL073101NHLBI NIH HHS R01 HL107910NHLBI NIH HHS R01-HL107910NHLBI NIH HHS R01-HL73101
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Coronary CirculationDiabetes Mellitus, Type 2Diabetic AngiopathiesFemaleHumansMaleMicrocirculationMineralocorticoid Receptor AntagonistsSpironolactoneMineralocorticoid Receptor AntagonistsSpironolactone

Identifiers

PMID25538279
PMCPMC4274807

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.