Evidence map›Paper›PMID 25537797›Full record

ArticleInflammation2015

Comparison of the effects of aerobic conditioning before and after pulmonary allergic inflammation.

Ronaldo Aparecido da Silva, Francine Maria Almeida, Clarice Rosa Olivo, Beatriz Mangueira Saraiva-Romanholo, Adenir Perini, Milton Arruda Martins, Celso Ricardo Fernandes Carvalho

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Inflammation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03311048 (Airway Inflammatory Profile Among Cleaning Workers From Different Workplaces), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03311048 nacompletednot on this map

Airway Inflammatory Profile Among Cleaning Workers From Different Workplaces

TypeinterventionalSponsorUniversity of Sao PauloRan2015 to 2017Enrolled167ConditionsInflammation, Work Related Illnesses, Symptoms and Signs, Asthma, OccupationalArmsNasal swab, Questionnaires
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ronaldo Aparecido da SilvaDepartment of Physical Therapy, University of Sao Paulo, São Paulo, Brazil.
Francine Maria Almeida
Clarice Rosa Olivo
Beatriz Mangueira Saraiva-Romanholo
Adenir Perini
Milton Arruda Martins
Celso Ricardo Fernandes Carvalho
Universidade de São Paulo · BRUniversidade Cidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study is to compare the effects of aerobic conditioning (AC) before (ACBS) and after (ACAS) allergic sensitization. BALB/c mice were divided into two main groups: ACBS and ACAS. Each groups was divided into subgroups: control (nonsensitized/nontrained), AC (nonsensitized/trained), ovalbumin (OVA) (sensitized/nontrained), AC+OVA (trained/sensitized), and OVA+AC (sensitized/trained). Sensitization was induced using OVA and AC performed in treadmill (moderate intensity). We examined IgE and IgG1 levels, eosinophil counting, expression of Th1 (interleukin (IL)-2, IFN-α) and Th2 cytokines (IL-4, IL-5, IL-13), IL-10, vascular endothelial growth factor (VEGF), and airway remodeling. IgE and IgG1 were decreased only when exercise was performed before sensitization (ACBS); however, there was a decrease of eosinophils, Th2 cytokines, VEGF, and airway remodeling and increase in IL-10 in either ACBS or ACAS groups. Our results demonstrate that aerobic conditioning reduces Th2 response before and after sensitization by increasing IL-10 while the production of anaphylactic antibodies is reduced only when exercise is performed before sensitization.

Indexed as

Physical Conditioning, AnimalAirway RemodelingAnimalsAsthmaDisease Models, AnimalImmunoglobulin EImmunoglobulin GInterleukin-10Interleukin-13Interleukin-2Interleukin-4LungMaleMiceMice, Inbred BALB COvalbuminIL10 protein, mouseImmunoglobulin EImmunoglobulin GInterleukin-10Interleukin-13Interleukin-2Interleukin-4OvalbuminVascular Endothelial Growth Factor Avascular endothelial growth factor A, mouse

Identifiers

PMID25537797
OpenAlexW2156150785

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.