ArticleJournal of neurogastroenterology and motility2015
Risk factors for postoperative ileus following orthopedic surgery: the role of chronic constipation.
Article in Journal of neurogastroenterology and motility, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06862986 (The Effect of Ear Massage on Bowel Activity in Patients Undergoing Lower Extremity Surgery), which is not on this map. Cited by 24 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Ear Massage on Bowel Activity in Patients Undergoing Lower Extremity Surgery: A Randomized Controlled Study
Who cites it
24 citing papers in PubMed, 43 citations in OpenAlex.
- Effect of Chewing Gum on Bowel Function Recovery in Elderly Patients Following Posterior Lumbar Fusion Surgery: A Randomized Controlled Trial.Orthopaedic surgery · 2026Trial
- Enhanced Recovery after Surgery Protocol Accelerates Recovery of Lumbar Disc Herniation among Elderly Patients Undergoing Discectomy via Promoting Gastrointestinal Function.Pain research & managementTrial
- Early postoperative hypophosphatemia is an independent predictor of ileus after transforaminal lumbar interbody fusion: a multicenter retrospective cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Reducing paralytic ileus after radical cystectomy: The role of advanced haemodynamic monitoring.BJUI compass · 2026Article
- Preoperative Evaluation of the Child With Cerebral Palsy.Journal of the Pediatric Orthopaedic Society of North America · 2026Review
- Prophylactic laxative use for postoperative constipation in urological cancer: a real-world cohort study.World journal of urology · 2025Article
- Association of Postoperative Ileus With Length of Hospital Stay in Abdominal Surgery Patients.Cureus · 2025Article
- Postoperative ileus and associated factors in patients following major abdominal surgery in Ethiopia: a prospective cohort study.BMC surgery · 2025Article
- Validity of the I‑FEED classification in assessing postoperative gastrointestinal impairment in patients undergoing elective lumbar spinal surgery with general anesthesia: a prospective observational study.Perioperative medicine (London, England) · 2024Article
- Risk Factors for Postoperative Ileus in Patients Undergoing Spine Surgery.Global spine journal · 2023Article
- A standardized postoperative bowel regimen protocol after spine surgery.Frontiers in surgery · 2023Article
- What Are Risk Factors for an Ileus After Posterior Spine Surgery?-A Case Control Study.Global spine journal · 2022Article
- Clinical Importance, Incidence and Risk Factors for the Development of Postoperative Ileus Following Adult Spinal Deformity Surgery.Global spine journal · 2022Article
- Laxative use and mortality in patients on haemodialysis: a prospective cohort study.BMC nephrology · 2021Article
- Defecation delay in patients after lung tumor surgery: a prospective nested case-control study.Annals of translational medicine · 2021Article
- Bowel dysfunction after elective spinal surgery: etiology, diagnostics and management based on the medical literature and experience in a university hospital.Der Orthopade · 2021Review
- Incidence and Risk of Severe Ileus After Orthopedic Surgery: A Case-Control Study.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2020Article
- Paralytic ileus in the United States: A cross-sectional study from the national inpatient sample.SAGE open medicine · 2020Article
- Systemic Complications and Radiographic Findings of Opioid Use and Misuse: An Overview for Orthopedic Surgeons.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2019Review
- Risk Factors for Postoperative Ileus after Scoliosis Surgery.Spine surgery and related research · 2018Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimsDistinction is vague between severe constipation and postoperative ileus (POI) in terms of pathogenesis, clinical features, and treatment options. However, no data are available regarding their associations.
methodsAfter retrospective review of data from patients who underwent orthopedic surgery during the first 6 months of 2011, a total of 612 patients were included. Severe constipation was defined as symptoms of constipation requiring treatment using at least 2 laxatives from different classes for at least 6 months. POI was defined as paralytic ileus lasting more than 3 days post-surgery and associated with 2 or more of the following: (1) nausea/vomiting, (2) inability to tolerate an oral diet over a 24-hour period, and (3) absence of flatus over a 24-hour period. The subjects were divided into non-POI and POI groups, and we com - pared patient-, surgery-, and pharmaceutical-related factors.
resultsThirteen (2.1%) out of 612 experienced POI. In comparisons between the non-POI and POI groups, univariate analysis showed significant differences in the mean age (51.4 vs. 71.6 years), mean body mass index (24.1 vs. 21.8 kg/m(2)), severe constipation (5.8% vs. 76.9%), co-morbidities (33.2% vs. 84.6%), type of orthopedic surgery (spine/hip/limb: 19.4/11.0/65.6% vs. 23.1/61.5/15.4%), and estimated blood loss (50 vs. 300 mL). Multivariate logistic regression analysis, after adjustment for age, body mass index, co-morbidities, type of orthopedic surgery, and estimated blood loss, showed that severe constipation was an independent risk factor for POI (OR 35.23; 95% CI, 7.72-160.82; P < 0.001).
conclusionsSevere constipation is associated with POI after orthopedic surgery.
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