ArticleJournal of the American Heart Association2014
Gender differences in health status and adverse outcomes among patients with peripheral arterial disease.
Article in Journal of the American Heart Association, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 37 citations in OpenAlex.
- Not all mental disorders matter equally in peripheral arterial disease: Dementia drives prognosis and care disparities.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Review
- Role of Depression and Anxiety in Peripheral Artery Disease: Correlates, Outcomes, and Considerations for Treatment.Arteriosclerosis, thrombosis, and vascular biology · 2026Review
- Mortality rate in patients with symptomatic peripheral artery disease in Brazil: comparison between sexes.Einstein (Sao Paulo, Brazil) · 2025Article
- Addressing Psychosocial Care Needs in Women with Peripheral Artery Disease.Current cardiology reports · 2024Review
- The Pink Tax: Sex and Gender Disparities in Peripheral Artery Disease.US cardiology · 2024Review
- Dietary antioxidant intake increases ankle brachial pressure index in men but not in women: a cross-sectional study.Frontiers in cardiovascular medicine · 2024Article
- Women, lipids, and atherosclerotic cardiovascular disease: a call to action from the European Atherosclerosis Society.European heart journal · 2023Article
- Sex-Based Differences in Clinical Characteristics and Outcomes among Patients with Peripheral Artery Disease: A Retrospective Analysis.Journal of clinical medicine · 2023Article
- Quality of life for patients with in-stent restenosis after interventional therapy of peripheral artery disease.Revista da Associacao Medica Brasileira (1992) · 2023Article
- Sex as a Key Determinant of Peripheral Artery Disease: Epidemiology, Differential Outcomes, and Proposed Biological Mechanisms.The Canadian journal of cardiology · 2022Review
- Sex Differences in Peripheral Artery Disease.Circulation research · 2022Review
- Sex Differences in Trends and In-Hospital Outcomes Among Patients With Critical Limb Ischemia: A Nationwide Analysis.Journal of the American Heart Association · 2021Article
- Gender variation in symptomatic peripheral arterial occlusive disease among type-2 diabetic patients.SAGE open medicine · 2019Article
- Peripheral Arterial Disease in Women: an Overview of Risk Factor Profile, Clinical Features, and Outcomes.Current atherosclerosis reports · 2018Review
- Sex-Based Assessment of Patient Presentation, Lesion Characteristics, and Treatment Modalities in Patients Undergoing Peripheral Vascular Intervention.Circulation. Cardiovascular interventions · 2018Article
- Understanding sex differences in health status: A frontier in the field of vascular medicine.Vascular medicine (London, England) · 2017Article
- Food Insecurity and Peripheral Arterial Disease in Older Adult Populations.The journal of nutrition, health & aging · 2016Article
- Disparities in Perceived Physical and Mental Wellness: Relationships Between Social Vulnerability, Cardiovascular Risk Factor Prevalence, and Health Behaviors Among Elderly US Residents.Journal of primary care & community healthArticle
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFew studies have examined gender differences in health status and cardiovascular outcomes in patients with peripheral artery disease (PAD). This study assessed (1) self-reported health status at PAD diagnosis and 12-months later, and explored (2) whether outcomes in women with PAD differ with regard to long-term major adverse events. METHODS AND
resultsA total of 816 patients (285 women) with PAD were enrolled from 2 vascular clinics in the Netherlands. Baseline clinical data and subsequent adverse events were recorded and patients completed the Short Form-12 (SF-12, Physical Component Score [PCS] and Mental Component Score [MCS]) upon PAD diagnosis and 12-months later. Women had similar ages and clinical characteristics, but poorer socio-economic status and more depressive symptoms at initial diagnosis, as compared with men. Women also had poorer physical (PCS: 37±10 versus 40±10, P=0.004) and mental ( MCS: 47±12 versus 49±11, P=0.005) health status at the time of presentation. At 12-months, women still reported a poorer overall PCS score (41±12 versus 46±11, P=0.006) and MCS score (42±14 versus 49±12, P=0.002). Female gender was an independent determinant of a poorer baseline and 12-month PCS and MCS scores. However, there were no significant differences by gender on either mortality (unadjusted hazard ratio [HR]=0.93, 95% CI 0.60;1.44, P=0.74) or major adverse events (unadjusted HR=0.90, 95% CI 0.63;1.29, P=0.57), after a median follow-up of 3.2 years.
conclusionsWomen's physical and mental health status is compromised both at initial PAD diagnosis and at 12-month follow-up, despite experiencing a similar magnitude of change in their health scores throughout the first 12-months after diagnosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.