ArticlePloS one2014
Early mortality and primary causes of death in mothers of children with intellectual disability or autism spectrum disorder: a retrospective cohort study.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Mortality in Persons With Autism Spectrum Disorder or Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-analysis.JAMA pediatrics · 2022Pooled it
- Transcriptomic metaanalyses of autistic brains reveals shared gene expression and biological pathway abnormalities with cancer.Molecular autism · 2019Pooled it
- Resilience Within Families of Young Children with ASD.Journal of autism and developmental disorders · 2026Article
- Holes in holistic care after discharge of complex NICU infants - the gaps Hurt.Pediatric research · 2026Article
- The impact of sleep disorders of children with severe medical complexity on their caregivers' sleep: a perspective from two pediatric palliative care centers.Italian journal of pediatrics · 2026Article
- Parental Stress and Quality of Life in Parents of Young Children with Autism.Child psychiatry and human development · 2026Article
- Social capital and quality of life among caregivers of children with Autism Spectrum Disorder in Mongolia: a cross-sectional study.BMC public health · 2025Article
- Patient stratification reveals the molecular basis of disease co-occurrences.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Perceived Social Support Among Parents and Exploration of Challenges Faced by Single Mothers of Children with Neurodevelopmental Disorders-A Mixed Method Study.Annals of neurosciences · 2025Article
- Age-related trajectories of health and cognition in mothers of children with developmental disabilities: Longitudinal findings from two independent studies.Social science & medicine (1982) · 2025Article
- Maternal caregiving stress and metabolic health: Sexual activity as a potential buffer.Psychoneuroendocrinology · 2024Article
- Stress, Eating Behavior and Adverse Health in Parents of Young Children with Autism Spectrum Disorder.Journal of autism and developmental disorders · 2024Article
- Psychological, behavioural, and physical aspects of caregiver strain in autism-caregivers: a cohort study.EClinicalMedicine · 2023Article
- Caring for Children with an Autism Spectrum Disorder: Factors Associating with Health- and Care-Related Quality of Life of the Caregivers.Journal of autism and developmental disorders · 2022Article
- Stress, anxiety and depression in parents of children with autism spectrum disorders in Kazakhstan: prevalence and associated factors.Global mental health (Cambridge, England) · 2022Article
- Validity and Reliability of the Caregiving Difficulty Scale in Mothers of Children with Cerebral Palsy.International journal of environmental research and public health · 2021Article
- Article
- Interest in Research Participation Among Caregivers of Children with Neurodevelopmental Disorders.Journal of autism and developmental disorders · 2019Article
- Four Social Brain Regions, Their Dysfunctions, and Sequelae, Extensively Explain Autism Spectrum Disorder Symptomatology.Brain sciences · 2019Article
- Predictors of Satisfaction with Life in Parents of Children with Autism Spectrum Disorder.Journal of autism and developmental disorders · 2018Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionMothers of children with intellectual disability or autism spectrum disorder (ASD) have poorer health than other mothers. Yet no research has explored whether this poorer health is reflected in mortality rates or whether certain causes of death are more likely. We aimed to calculate the hazard ratios for death and for the primary causes of death in mothers of children with intellectual disability or ASD compared to other mothers.
methodsThe study population comprised all mothers of live-born children in Western Australia from 1983-2005. We accessed state-wide databases which enabled us to link socio-demographic details, birth dates, diagnoses of intellectual disability or ASD in the children and dates and causes of death for all mothers who had died prior to 2011. Using Cox Regression with death by any cause and death by each of the three primary causes as the event of interest, we calculated hazard ratios for death for mothers of children intellectual disability or ASD compared to other mothers. RESULTS AND DISCUSSION: During the study period, mothers of children with intellectual disability or ASD had more than twice the risk of death. Mothers of children with intellectual disability were 40% more likely to die of cancer; 150% more likely to die of cardiovascular disease and nearly 200% more likely to die from misadventure than other mothers. Due to small numbers, only hazard ratios for cancer were calculated for mothers of children with ASD. These mothers were about 50% more likely to die from cancer than other mothers. Possible causes and implications of our results are discussed.
conclusionSimilar studies, pooling data from registries elsewhere, would improve our understanding of factors increasing the mortality of mothers of children with intellectual disability or ASD. This would allow the implementation of informed services and interventions to improve these mothers' longevity.
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