ArticleReports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology2015
Brain metastases from stomach cancer - The role of different treatment modalities and efficacy of palliative radiotherapy.
Article in Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical outcome and molecular characterization of brain metastases from esophageal and gastric cancer: a systematic review.Medical oncology (Northwood, London, England) · 2017Pooled it
- Risk of central nervous system metastasis and survival in HER2+ positive breast and non-breast cancers.Neuro-oncology practice · 2025Article
- Survival and Treatment Outcomes in Gastric Cancer Patients with Brain Metastases: A Systematic Review and Meta-Analysis.Cancers · 2024Review
- Metastasis patterns and prognosis in patients with gastric cancer: a Surveillance, Epidemiology, and End Results-based analysis.Journal of gastrointestinal oncology · 2024Article
- Gastric Cancer With Brain Metastasis: A Case Report.Cureus · 2023Article
- Analysis of risk factors and prognostic factors of brain metastasis in gastric cancer: a surveillance, epidemiology and end-results database study.Scientific reports · 2023Article
- Stereotactic radiosurgery for patients with brain metastases from gastroesophageal cancers.Journal of neuro-oncology · 2023Article
- Pachymeningeal en plaque metastasis from gastric cancer mimicking subdural hematoma: illustrative case.Journal of neurosurgery. Case lessons · 2023Article
- Real-world clinical outcomes of the combination of anti-PD-1 antibody, trastuzumab, and chemotherapy for HER2-positive gastric/gastroesophageal junction cancer.Cancer medicine · 2023Article
- HER2-Positive Gastroesophageal Cancers Are Associated with a Higher Risk of Brain Metastasis.Cancers · 2022Article
- Current status of gastrointestinal tract cancer brain metastasis and the use of blood-based cancer biomarker biopsy.Clinical & experimental metastasis · 2022Review
- Brain metastasis from gastric adenocarcinoma: A large comprehensive population-based cohort study on risk factors and prognosis.Frontiers in oncology · 2022Article
- Successful Treatment of Advanced Gastric Cancer with Brain Metastases through an Abscopal Effect by Radiation and Immune Checkpoint Inhibitor Therapy.Journal of gastric cancer · 2021Article
- A Rare Occurrence of Isolated Brain Metastases from Gastric Cancer.Case reports in medicine · 2019Article
- Brain metastasis in gastroesophageal adenocarcinoma and HER2 status.Journal of neuro-oncology · 2018Article
- Palliative whole-brain radiotherapy and health- related quality of life for patients with brain metastasis in cancer.Neuropsychiatric disease and treatment · 2015Article
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2 authors.
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Abstract
aimTo evaluate different treatment modalities, sequences, and prognostic factors in patients with brain metastases from stomach cancer.
backgroundBrain metastases from gastric cancer are rare and late manifestation of the disease, occurring in less than 1% of gastric cancer patients. The prognosis is poor and median overall survival is 1.3-2.4 months. The standard treatment scheme has not yet been described. Most studies present small sample sizes. The choice of treatment scheme is individually based on performance status, number, location and size of metastases, the status of primary tumor and the presence of other metastases. MATERIALS AND
methodsSixteen patients diagnosed with brain metastases from gastric cancer in Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch. Patients, mostly men (69%) aged 51-75 years, (median 68.5 years). Thirteen (81.25%) had treatment of primary tumor before diagnosis of brain metastases. Primary metastatic gastric cancer was diagnosed in 6 patients (37.5%), in 3 cases (18.75%) brain was the site of those metastases. Treatment schemes were individually based.
resultsWe identified prognostic factors influencing OS: performance status, number of brain metastases, type of treatment. Median OS was 2.8 months. Median time to brain metastases was 12.3 months and it was shorter in patients with pretreatment metastases to other organs. Patients treated with combined treatment had median survival of 12.3 months.
conclusionsAggressive treatment schemes are needed to improve the outcome. Prognostic factors such as performance status, number of metastases, dissemination to other organs are helpful in considering the best treatment options.
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