ArticleJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences2014
Prevalence of hypertension and type 2 diabetes mellitus in patients with colorectal cancer and their median survival time: A cohort study.
Article in Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 30 citations in OpenAlex.
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- Hypertension and Its Associated Factors Among Cancer Patients at University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia: Hospital-Based Cross-Sectional Study.Journal of multidisciplinary healthcare · 2022Article
- Perioperative mortality of head and neck cancers.BMC cancer · 2021Article
- Risk of Parkinson's disease after colectomy: longitudinal follow-up study using a national sample cohort.Journal of neurology · 2020Observational
- Mixture cure model for estimating short-term and long-term colorectal cancer survival.Gastroenterology and hepatology from bed to bench · 2019Article
- Article
- Evaluation of observed and the expected incidence of common cancers: An experience from Southwestern of Iran, 2010-2014.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2018Article
- Comparing of Cox model and parametric models in analysis of effective factors on event time of neuropathy in patients with type 2 diabetes.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2017Article
- Risk factors for heart failure in a cohort of patients with newly diagnosed myocardial infarction: a matched, case-control study in Iran.Epidemiology and health · 2016Article
- Modeling of in hospital mortality determinants in myocardial infarction patients, with and without stroke: A national study in Iran.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2016Article
- Modeling of the relationship between the environmental air pollution, clinical risk factors, and hospital mortality due to myocardial infarction in Isfahan, Iran.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2015Article
- Spatial analysis of myocardial infarction in Iran: National report from the Iranian myocardial infarction registry.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2015Article
- Effect of metabolic syndrome and its components on survival in colorectal cancer: a prospective study.Journal of renal injury prevention · 2015Article
- Predictive Factors of Hospital Mortality Due to Myocardial Infarction: A Multilevel Analysis of Iran's National Data.International journal of preventive medicine · 2015Article
- Effect of sour tea (Lipicom) pill versus captopril on the treatment of hypertension.Journal of renal injury prevention · 2015Article
- Important statistical points to improve and promote the methodology of the articles on medical sciences, particularly nephrology and kidney; a review article.Journal of renal injury prevention · 2015Review
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundType 2 diabetes mellitus (DM) and hypertension are worldwide epidemic. Association between DM and colon cancer was obtained in previous studies. Prevalence of DM and hypertension in the patients with colorectal cancer (CRC) has not been reported in Iran. The present study was aimed to investigate the prevalence of hypertension and type 2 DM and their effect on median survival time in patients with CRC. MATERIALS AND
methodsOverall, 2570 individual-year follow-ups were conducted for 1127 patients with CRC. For the diagnosis of type 2 DM, fasting blood sugar test and glycosylated hemoglobin test were used and for hypertension, blood pressure was measured in two turns. The descriptive indices were calculated, and the mean and median survival from CRC diagnosis time was calculated using survival analysis and a comparison among survival times was done through log-rank test. Stata software 12 (Stata Corp. 2011. Stata Statistical Software: Release 12. College Station, TX: Stata Corp LP) was used for data analysis.
resultsThe prevalence of hypertension and type 2 DM in the patients with CRC was respectively 13.38% (95% confidence interval [CI]: 11.1-15.8) and 8.69% (95% CI: 7-10.7). Median survival time in patients with hypertension and DM were 8.52 and 4.9 years. According to log-rank test, no significant difference was observed between the survival time of CRC patients suffering from hypertension and diabetes type 2.
conclusionThe obtained findings in this study indicate that survival time in patients with type 2 DM less than hypertension but two metabolic diseases have the same effect on survival rate of the patients with CRC. Understanding the risk factors for CRC may guide the development of strategies targeted toward its prevention.
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25535499PMC4268193W45004542What OpenQuestion holds
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