ArticleThe American journal of tropical medicine and hygiene2015
Genetic characterization of Echinococcus granulosus from a large number of formalin-fixed, paraffin-embedded tissue samples of human isolates in Iran.
Article in The American journal of tropical medicine and hygiene, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Echinococcus granulosus sensu lato Genotypes in Different Hosts Worldwide: A Systematic Review.Acta parasitologica · 2022Pooled it
- A systematic review and meta-analysis of the genetic characterization of human echinococcosis in Iran, an endemic country.Epidemiology and health · 2019Pooled it
- Frequency and Genetic Characterization ofJournal of parasitology research · 2026Article
- Environmental contamination with feces of free-roaming dogs and the risk of transmission of Echinococcus and Taenia species in urban regions of southeastern Iran.Parasites & vectors · 2024Article
- Genetic Characterization ofDiseases (Basel, Switzerland) · 2023Article
- Comparison of Isoenzyme Pattern of Echinococcus granulosus sensu stricto (G1-G3) and E. canadensis (G6/G7) ProtoscolecesIranian biomedical journal · 2023Article
- Genetic characterization of human echinococcosis in Southern Punjab, Pakistan.Frontiers in cellular and infection microbiology · 2023Article
- Genotyping and Identification of Antigen B Gene Polymorphism ofBalkan medical journal · 2022Article
- Echinococcoses in Iran, Turkey, and Pakistan: Old Diseases in the New Millennium.Clinical microbiology reviews · 2021Article
- Genetic Characterization of Echinococcus granulosus Sensu Lato in Livestock and Human Isolates from North of Iran Indicates the Presence of E. ortleppi in Cattle.Acta parasitologica · 2021Article
- Cystic echinococcosis in sheep and goats of Lebanon.Parasitology · 2021Article
- Molecular Characterization ofPathogens (Basel, Switzerland) · 2020Article
- Cystic Echinococcosis of Camels: 12S rRNA Gene Variation Revealed Changing Pattern of Genetic Diversity WithinFrontiers in veterinary science · 2020Article
- Echinococcus multilocularis and Echinococcus granulosus in canines in North-Khorasan Province, northeastern Iran, identified using morphology and genetic characterization of mitochondrial DNA.Parasites & vectors · 2019Article
- Genotyping ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2019Article
- Prevalence and risk factors associated with human cystic echinococcosis in Iran.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2019Article
- Epidemiological and molecular studies onVeterinary world · 2019Article
- Article
- A conventional PCR for differentiating common taeniid species of dogs based on in silico microsatellite analysis.Revista do Instituto de Medicina Tropical de Sao Paulo · 2017Article
- First report of Tasmanian sheep strain (G2) genotype isolated from Iranian goat using the high resolution melting (HRM) analysis.Gastroenterology and hepatology from bed to bench · 2016Article
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Authors and funding
7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Cystic echinococcosis (CE), caused by the larval stage of Echinococcus granulosus, presents an important medical and veterinary problem globally, including that in Iran. Different genotypes of E. granulosus have been reported from human isolates worldwide. This study identifies the genotype of the parasite responsible for human hydatidosis in three provinces of Iran using formalin-fixed paraffin-embedded tissue samples. In this study, 200 formalin-fixed paraffin-embedded tissue samples from human CE cases were collected from Alborz, Tehran, and Kerman provinces. Polymerase chain reaction amplification and sequencing of the partial mitochondrial cytochrome c oxidase subunit 1 gene were performed for genetic characterization of the samples. Phylogenetic analysis of the isolates from this study and reference sequences of different genotypes was done using a maximum likelihood method. In total, 54.4%, 0.8%, 1%, and 40.8% of the samples were identified as the G1, G2, G3, and G6 genotypes, respectively. The findings of the current study confirm the G1 genotype (sheep strain) to be the most prevalent genotype involved in human CE cases in Iran and indicates the high prevalence of the G6 genotype with a high infectivity for humans. Furthermore, this study illustrates the first documented human CE case in Iran infected with the G2 genotype.
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