Evidence map›Paper›PMID 25534981›Full record

ReviewJournal of vascular surgery2015

Advancing beyond the "heart-healthy diet" for peripheral arterial disease.

Emily V Nosova, Michael S Conte, S Marlene Grenon

Open access · greenAbstract readReview
In one paragraph

Review in Journal of vascular surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Guideline
  2. Sex-Specific Multimorbidity-Multibehaviour Patterns in Primary Care Populations.International journal of environmental research and public health · 2025
    Observational
  3. Article
  4. Impact of BMI on Recovery and Quality of Life Post-Revascularization in Peripheral Arterial Disease Patients.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Observational
  12. Article
  13. Article
  14. Global Vascular Guidelines on the Management of Chronic Limb-Threatening Ischemia.European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery · 2019
    Article
  15. Article
  16. Article
  17. Review
  18. Management of Peripheral Arterial Disease: Lifestyle Modifications and Medical Therapies.Journal of the Society for Cardiovascular Angiography & Interventions
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Emily V NosovaDepartment of Surgery, University of California, San Francisco, Calif; VIPERx Laboratory, San Francisco, Calif.
Michael S ConteDepartment of Surgery, University of California, San Francisco, Calif; Cardiovascular Research Institute, University of California, San Francisco, Calif.
S Marlene GrenonDepartment of Surgery, University of California, San Francisco, Calif; VIPERx Laboratory, San Francisco, Calif; Department of Surgery, San Francisco Veterans Affairs Medical Center, San Francisco, Calif. Electronic address: marlene.grenon@ucsfmedctr.org.
University of California, San Francisco · USSan Francisco VA Medical Center · US

Funding

Effects of fish oil on inflammation and vascular function in claudicantsK23HL122446 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRENON, MARLENE · 2014 to 2017
$806k
NHLBI NIH HHS K23 HL122446
6 · The paper itself

Abstract

objectivePeripheral arterial disease (PAD) is a burdensome cardiovascular condition that results from chronic inflammatory insults to the arterial vasculature. Key risk factors include age, gender, type 2 diabetes mellitus, hypertension, hypercholesterolemia, hyperhomocysteinemia, smoking, lack of physical fitness, and poor diet, the latter three being modifiable in the development and progression of PAD. A growing body of evidence indicates that imbalanced nutrient intake may contribute to the development and progression of PAD. The purpose of this review is to summarize current knowledge about nutritional patterns among patients with PAD and to ascertain whether certain health-promoting foods and nutrients could benefit patients with this condition.

methodsWe conducted a comprehensive literature review to examine primary source evidence for or against the nutrients that are commonly associated with PAD and their potential utility as therapies.

resultsWe summarized nine categories of nutrients, as well as four diets endorsed by the American Heart Association that may be prescribed to patients with or at risk for PAD. The nutrients reviewed included omega-3 polyunsaturated fatty acids (n-3 PUFAs), folate and B-series vitamins, and antioxidants. The diet plans described include the Dietary Approaches to Stop Hypertension (DASH) diet, Mediterranean diet, low-fat diet, low carbohydrate diet, Dr Dean Ornish's Spectrum Diet and Dr Andrew Weil's Anti-Inflammatory Diet.

conclusionsPAD is a chronic inflammatory condition that is associated with longstanding poor nutrition habits. We advocate for an intensified use of diet in PAD therapy, and we specifically recommend following eating patterns that are rich in nutrients with anti-inflammatory and antioxidant properties.

Indexed as

Dietary SupplementsLife StyleNutritional StatusRisk Reduction BehaviorDietHumansPeripheral Arterial DiseaseRecommended Dietary AllowancesRisk FactorsTreatment Outcome

Identifiers

PMID25534981
PMCPMC4275620
OpenAlexW2058688409

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.