ReviewNature reviews. Microbiology2015
Polintons: a hotbed of eukaryotic virus, transposon and plasmid evolution.
Review in Nature reviews. Microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 121 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
121 citing papers in PubMed, 221 citations in OpenAlex.
- Infection cycles of viruses of the phylum Nucleocytoviricota.Nature reviews. Microbiology · 2026Review
- Why did some viruses evolve to be giants while others did not?Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Evidence that Zymocin-Like Killer Plasmids Were Present in the Common Ancestor of Terrestrial Fungi.Genome biology and evolution · 2026Article
- Unveiling the cryptic diversity and distribution of elements related to virophage mavirus through deep mining of pPolB proteins.Virologica Sinica · 2026Article
- Structural studies promote vaccine development: lessons from African swine fever virus.Protein & cell · 2026Article
- A Polinton-like Virus ofViruses · 2026Article
- From sequencing to understanding: a grand challenge in genome-scale molecular and genetic analysis.Frontiers in plant science · 2026Article
- Endogenized polinton-like viruses in the dinoflagellateThe Journal of general virology · 2025Article
- Lineage-specific expansions of polinton-like viruses in photosynthetic cryptophytes.Microbiome · 2025Article
- Double-stranded DNA viruses may serve as vectors for horizontal transfer of intron-generating transposons.Mobile DNA · 2025Article
- Evolution of ubiquitin, cytoskeleton, and vesicular trafficking machinery in giant viruses.Journal of virology · 2025Article
- Expanding the Diversity ofViruses · 2025Article
- Article
- Pipolins are bimodular platforms that maintain a reservoir of defense systems exchangeable with various bacterial genetic mobile elements.Nucleic acids research · 2024Article
- The polinton-like supergroup of viruses: evolution, molecular biology, and taxonomy.Microbiology and molecular biology reviews : MMBR · 2024Review
- DNA polymerase swapping in Caudoviricetes bacteriophages.Virology journal · 2024Article
- Article
- DNA methylation enables recurrent endogenization of giant viruses in an animal relative.Science advances · 2024Article
- Natural history of eukaryotic DNA viruses with double jelly-roll major capsid proteins.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- A novel approach to exploring the dark genome and its application to mapping of the vertebrate virus fossil record.Genome biology · 2024Article
61 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
Polintons (also known as Mavericks) are large DNA transposons that are widespread in the genomes of eukaryotes. We have recently shown that Polintons encode virus capsid proteins, which suggests that these transposons might form virions, at least under some conditions. In this Opinion article, we delineate the evolutionary relationships among bacterial tectiviruses, Polintons, adenoviruses, virophages, large and giant DNA viruses of eukaryotes of the proposed order 'Megavirales', and linear mitochondrial and cytoplasmic plasmids. We hypothesize that Polintons were the first group of eukaryotic double-stranded DNA viruses to evolve from bacteriophages and that they gave rise to most large DNA viruses of eukaryotes and various other selfish genetic elements.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.