ArticleMolecular biology and evolution2015
Degeneration of the nonrecombining regions in the mating-type chromosomes of the anther-smut fungi.
Article in Molecular biology and evolution, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 60 citations in OpenAlex.
- Homothallic or Heterothallic? A Genomic Investigation Into the Sexual Capabilities of the Ascomycete Fungus Clonostachys rosea.Molecular ecology · 2026Article
- Repeated loss of function at HD mating-type genes and of recombination in anther-smut fungi.Nature communications · 2025Article
- Genome biology and evolution of mating-type loci in four cereal rust fungi.PLoS genetics · 2024Article
- Dynamics of transposable element accumulation in the non-recombining regions of mating-type chromosomes in anther-smut fungi.Nature communications · 2023Article
- Stepwise recombination suppression around the mating-type locus in an ascomycete fungus with self-fertile spores.PLoS genetics · 2023Article
- Tempo of Degeneration Across Independently Evolved Nonrecombining Regions.Molecular biology and evolution · 2022Article
- Review
- Evolutionary Genomics of Sex-Related Chromosomes at the Base of the Green Lineage.Genome biology and evolution · 2021Article
- Recombination suppression and evolutionary strata around mating-type loci in fungi: documenting patterns and understanding evolutionary and mechanistic causes.The New phytologist · 2021Review
- Pervasive Phenotypic Impact of a Large Nonrecombining Introgressed Region in Yeast.Molecular biology and evolution · 2020Article
- Differential Gene Expression between Fungal Mating Types Is Associated with Sequence Degeneration.Genome biology and evolution · 2020Article
- Higher Gene Flow in Sex-Related Chromosomes than in Autosomes during Fungal Divergence.Molecular biology and evolution · 2020Article
- Fitness differences suppress the number of mating types in evolving isogamous species.Royal Society open science · 2020Article
- Little Evidence of Antagonistic Selection in the Evolutionary Strata of Fungal Mating-Type Chromosomes (G3 (Bethesda, Md.) · 2019Article
- Article
- Convergent evolution of complex genomic rearrangements in two fungal meiotic drive elements.Nature communications · 2018Article
- Multiple convergent supergene evolution events in mating-type chromosomes.Nature communications · 2018Article
- Gene Presence-Absence Polymorphism in Castrating Anther-Smut Fungi: Recent Gene Gains and Phylogeographic Structure.Genome biology and evolution · 2018Article
- Genetic Diversity on the Sex Chromosomes.Genome biology and evolution · 2018Review
- Article
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Authors and funding
16 authors at 8 institutions in 3 countries.
Funding
Abstract
Dimorphic mating-type chromosomes in fungi are excellent models for understanding the genomic consequences of recombination suppression. Their suppressed recombination and reduced effective population size are expected to limit the efficacy of natural selection, leading to genomic degeneration. Our aim was to identify the sequences of the mating-type chromosomes (a1 and a2) of the anther-smut fungi and to investigate degeneration in their nonrecombining regions. We used the haploid a1 Microbotryum lychnidis-dioicae reference genome sequence. The a1 and a2 mating-type chromosomes were both isolated electrophoretically and sequenced. Integration with restriction-digest optical maps identified regions of recombination and nonrecombination in the mating-type chromosomes. Genome sequence data were also obtained for 12 other Microbotryum species. We found strong evidence of degeneration across the genus in the nonrecombining regions of the mating-type chromosomes, with significantly higher rates of nonsynonymous substitution (dN/dS) than in nonmating-type chromosomes or in recombining regions of the mating-type chromosomes. The nonrecombining regions of the mating-type chromosomes also showed high transposable element content, weak gene expression, and gene losses. The levels of degeneration did not differ between the a1 and a2 mating-type chromosomes, consistent with the lack of homogametic/heterogametic asymmetry between them, and contrasting with X/Y or Z/W sex chromosomes.
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