Evidence map›Paper›PMID 25533660›Full record

ReviewViruses2014

Cetacean morbillivirus: current knowledge and future directions.

Marie-Françoise Van Bressem, Pádraig J Duignan, Ashley Banyard, Michelle Barbieri, Kathleen M Colegrove, Sylvain De Guise, Giovanni Di Guardo, Andrew Dobson, Mariano Domingo, Deborah Fauquier and 22 more

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
100citing papers in PubMed, 1 pooled it
11.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

100 citing papers in PubMed, 1 synthesis or guideline pooled it, 240 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Longitudinal Multimodal Monitoring of Eight Captive Beluga Whale (Animals : an open access journal from MDPI · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Animals : an open access journal from MDPI · 2025
    Article
  10. Article
  11. Article
  12. Article
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  15. Article
  16. Article
  17. Article
  18. Article
  19. First Detection of Gammacoronavirus in a Striped Dolphin (Animals : an open access journal from MDPI · 2024
    Article
  20. Article

40 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors at 20 institutions in 9 countries.

Marie-Françoise Van BressemCetacean Conservation Medicine Group (CMED), Peruvian Centre for Cetacean Research (CEPEC), Pucusana, Lima 20, Peru. mfb.cmed@gmail.com.
Pádraig J DuignanDepartment of Ecosystem and Public Health, University of Calgary, Calgary, AL T2N 4Z6, Canada. ppjduign@ucalgary.ca.
Ashley BanyardWildlife Zoonoses and Vector Borne Disease Research Group, Animal and Plant Health Agency (APHA), Weybridge, Surrey KT15 3NB, UK. ashley.banyard@apha.gsi.gov.uk.
Michelle BarbieriThe Marine Mammal Centre, Sausalito, CA 94965, USA. michelle.barbieri@noaa.gov.
Kathleen M ColegroveZoological Pathology Program, College of Veterinary Medicine, University of Illinois at Maywood, IL 60153 , USA. katie.colegrove@gmail.com.
Sylvain De GuiseDepartment of Pathobiology and Veterinary Science, and Connecticut Sea Grant College Program, University of Connecticut, Storrs, CT 06269, USA. sylvain.deguise@uconn.edu.
Giovanni Di GuardoFaculty of Veterinary Medicine, University of Teramo, 64100 Teramo, Italy. gdiguardo@unite.it.
Andrew DobsonDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA. dobson@princeton.edu.
Mariano DomingoCentre de Recerca en Sanitat Animal (CReSA), Autonomous University of Barcelona, Bellaterra, Barcelona 08193, Spain. Mariano.Domingo@cresa.uab.cat.
Deborah FauquierCetacean Conservation Medicine Group (CMED), Peruvian Centre for Cetacean Research (CEPEC), Pucusana, Lima 20, Peru.
Antonio FernandezCetacean Conservation Medicine Group (CMED), Peruvian Centre for Cetacean Research (CEPEC), Pucusana, Lima 20, Peru.
Tracey GoldsteinCetacean Conservation Medicine Group (CMED), Peruvian Centre for Cetacean Research (CEPEC), Pucusana, Lima 20, Peru. ppjduign@ucalgary.ca.
Bryan GrenfellDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA. grenfell@princeton.edu.
Kátia R GrochCetacean Conservation Medicine Group (CMED), Peruvian Centre for Cetacean Research (CEPEC), Pucusana, Lima 20, Peru. katie.colegrove@gmail.com.
Frances GullandThe Marine Mammal Centre, Sausalito, CA 94965, USA. sylvain.deguise@uconn.edu.
Brenda A JensenCetacean Conservation Medicine Group (CMED), Peruvian Centre for Cetacean Research (CEPEC), Pucusana, Lima 20, Peru. gdiguardo@unite.it.
Paul D JepsonCetacean Conservation Medicine Group (CMED), Peruvian Centre for Cetacean Research (CEPEC), Pucusana, Lima 20, Peru. paul.jepson@ioz.ac.uk.
Ailsa HallCetacean Conservation Medicine Group (CMED), Peruvian Centre for Cetacean Research (CEPEC), Pucusana, Lima 20, Peru. Mariano.Domingo@cresa.uab.cat.
Thijs KuikenDepartment of Ecosystem and Public Health, University of Calgary, Calgary, AL T2N 4Z6, Canada. ppjduign@ucalgary.ca.
Sandro MazzariolDepartment of Ecosystem and Public Health, University of Calgary, Calgary, AL T2N 4Z6, Canada. ppjduign@ucalgary.ca.
Sinead E MorrisDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA. semorris@princeton.edu.
Ole NielsenDepartment of Ecosystem and Public Health, University of Calgary, Calgary, AL T2N 4Z6, Canada. ppjduign@ucalgary.ca.
Juan A RagaDepartment of Ecosystem and Public Health, University of Calgary, Calgary, AL T2N 4Z6, Canada. ashley.banyard@apha.gsi.gov.uk.
Teresa K RowlesCetacean Conservation Medicine Group (CMED), Peruvian Centre for Cetacean Research (CEPEC), Pucusana, Lima 20, Peru.
Jeremy SalikiDepartment of Ecosystem and Public Health, University of Calgary, Calgary, AL T2N 4Z6, Canada. ppjduign@ucalgary.ca.
Eva SierraCetacean Conservation Medicine Group (CMED), Peruvian Centre for Cetacean Research (CEPEC), Pucusana, Lima 20, Peru.
Nahiid StephensDepartment of Ecosystem and Public Health, University of Calgary, Calgary, AL T2N 4Z6, Canada. katie.colegrove@gmail.com.
Brett StoneDepartment of Ecosystem and Public Health, University of Calgary, Calgary, AL T2N 4Z6, Canada. sylvain.deguise@uconn.edu.
Ikuko TomoDepartment of Ecosystem and Public Health, University of Calgary, Calgary, AL T2N 4Z6, Canada. gdiguardo@unite.it.
Jianning WangDepartment of Ecosystem and Public Health, University of Calgary, Calgary, AL T2N 4Z6, Canada. ppjduign@ucalgary.ca.
Thomas WaltzekDepartment of Ecosystem and Public Health, University of Calgary, Calgary, AL T2N 4Z6, Canada. Mariano.Domingo@cresa.uab.cat.
James F X WellehanWildlife Zoonoses and Vector Borne Disease Research Group, Animal and Plant Health Agency (APHA), Weybridge, Surrey KT15 3NB, UK. ashley.banyard@apha.gsi.gov.uk.
Marine Mammal Center · USNOAA National Marine Fisheries Service · USPrinceton University · USUniversidad de Las Palmas de Gran Canaria · ESUniversity of Florida · USAnimal and Plant Health Agency · GBCentro Peruano de Estudios Sociales · PECommonwealth Scientific and Industrial Research Organisation · AUErasmus MC · NLFisheries and Oceans Canada · CAHawaii Pacific University · USMurdoch University · AUNational Institutes of Health · USQueensland Police Service · AUSouth Australian Museum · AUUniversidade de São Paulo · BRUniversitat Autònoma de Barcelona · ESUniversitat de València · ESUniversity of Calgary · CAUniversity of California, Davis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We review the molecular and epidemiological characteristics of cetacean morbillivirus (CeMV) and the diagnosis and pathogenesis of associated disease, with six different strains detected in cetaceans worldwide. CeMV has caused epidemics with high mortality in odontocetes in Europe, the USA and Australia. It represents a distinct species within the Morbillivirus genus. Although most CeMV strains are phylogenetically closely related, recent data indicate that morbilliviruses recovered from Indo-Pacific bottlenose dolphins (Tursiops aduncus), from Western Australia, and a Guiana dolphin (Sotalia guianensis), from Brazil, are divergent. The signaling lymphocyte activation molecule (SLAM) cell receptor for CeMV has been characterized in cetaceans. It shares higher amino acid identity with the ruminant SLAM than with the receptors of carnivores or humans, reflecting the evolutionary history of these mammalian taxa. In Delphinidae, three amino acid substitutions may result in a higher affinity for the virus. Infection is diagnosed by histology, immunohistochemistry, virus isolation, RT-PCR, and serology. Classical CeMV-associated lesions include bronchointerstitial pneumonia, encephalitis, syncytia, and lymphoid depletion associated with immunosuppression. Cetaceans that survive the acute disease may develop fatal secondary infections and chronic encephalitis. Endemically infected, gregarious odontocetes probably serve as reservoirs and vectors. Transmission likely occurs through the inhalation of aerosolized virus but mother to fetus transmission was also reported.

Indexed as

AnimalsCetaceaMorbillivirusMorbillivirus InfectionsPhylogeny

Identifiers

PMID25533660
PMCPMC4276946
OpenAlexW2017714227

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.