Evidence map›Paper›PMID 25533614›Full record

ArticleDiagnostic microbiology and infectious disease2015

Improved serotype-specific dengue virus detection in Trinidad and Tobago using a multiplex, real-time RT-PCR.

Jesse J Waggoner, Nikita S D Sahadeo, Arianne Brown, Alisha Mohamed-Hadley, Dexter Hadley, Leslie Carrington, Christine V F Carrington, Benjamin A Pinsky

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostic microbiology and infectious disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jesse J WaggonerDepartment of Medicine, Division of Infectious Diseases, Stanford University School of Medicine, Stanford, CA, USA.
Nikita S D SahadeoDepartment of Pre-Clinical Studies, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.
Arianne BrownTrinidad Public Health Laboratory, Port of Spain, Trinidad and Tobago.
Alisha Mohamed-HadleyDepartment of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Dexter HadleyDepartment of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Leslie CarringtonTrinidad Public Health Laboratory, Port of Spain, Trinidad and Tobago.
Christine V F CarringtonDepartment of Pre-Clinical Studies, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.
Benjamin A PinskyDepartment of Medicine, Division of Infectious Diseases, Stanford University School of Medicine, Stanford, CA, USA; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA. Electronic address: bpinsky@stanford.edu.

Funding

Stanford Global Health Consortium: Innovation, Design, Evaluation, and ActionRC4TW008781 · FIC · STANFORD UNIVERSITY · PI BARRY, MICHELE · 2010 to 2010
$8.1M
EMERGING INFECTIOUS DISEASEST32AI007502 · NIAID · STANFORD UNIVERSITY · PI Prasanna Jagannathan, DAVID A. RELMAN · 1995 to 2026
$6.8M
CCR NIH HHS RC4 TW008781-01FIC NIH HHS RC4 TW008781NIAID NIH HHS 2T32AI007502-16A1NIAID NIH HHS T32 AI007502
6 · The paper itself

Abstract

Dengue virus (DENV) transmission occurs throughout the Caribbean, though laboratory confirmation and epidemiologic surveillance are limited by the availability of serotype-specific molecular diagnostics. In this study, we show that a serotype-specific DENV multiplex, real-time reverse transcriptase-PCR (RT-PCR) detected DENV RNA in significantly more samples (82/182) than a reference hemi-nested RT-PCR (57/182; P=0.01).

Indexed as

AdolescentAdultAgedChildChild, PreschoolDengueDengue VirusFemaleHumansMaleMiddle AgedMolecular Diagnostic TechniquesMultiplex Polymerase Chain ReactionReal-Time Polymerase Chain ReactionSensitivity and SpecificitySerogroupDengueMolecularPathology

Identifiers

PMID25533614
PMCPMC4297500

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.