Evidence map›Paper›PMID 25533010›Full record

SynthesisNutrients2014

Dietary magnesium intake and metabolic syndrome in the adult population: dose-response meta-analysis and meta-regression.

Sang-Yhun Ju, Whan-Seok Choi, Sun-Myeong Ock, Chul-Min Kim, Do-Hoon Kim

Registry-linked trialOpen access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in Nutrients, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02151227 (Association of Dietary Magnesium Intake and Circulating Magnesium Concentration With Metabolic Syndrome), which is not on this map. Cited by 26 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 4 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02151227 completednot on this map

Association of Dietary Magnesium Intake and Circulating Magnesium Concentration With Metabolic Syndrome: A Dose-response Meta-analysis

TypeobservationalSponsorThe Catholic University of KoreaRan2014 to 2014Enrolled12ConditionsMetabolic Syndrome X, Insulin Resistance Syndrome X, Metabolic Cardiovascular Syndrome, Dysmetabolic Syndrome X
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 4 syntheses or guidelines pooled it, 68 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Sang-Yhun JuDepartment of Family Medicine, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 10, 63-ro, Yeongdeungpo-gu, Seoul 150-713, Korea. kolpos@daum.net.
Whan-Seok ChoiDepartment of Family Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 22 Banpo-daero, Seocho-gu, Seoul 137-701, Korea. fmchs@dreamwiz.com.
Sun-Myeong OckDepartment of Family Medicine, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 10, 63-ro, Yeongdeungpo-gu, Seoul 150-713, Korea. soulfree@catholic.ac.kr.
Chul-Min KimDepartment of Family Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 22 Banpo-daero, Seocho-gu, Seoul 137-701, Korea. musofm@unitel.co.kr.
Do-Hoon KimDepartment of Family Medicine, Korea University Ansan Hospital, 516, Gojan 1-Dong, Danwon-Gu, Ansan-Si Gyeonggi-Do 425-707, Korea. kmcfm@hanmail.net.
Yeouido St. Mary's Hospital · KRKorea University · KRSeoul St. Mary's Hospital · KRSt. Mary's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ncreasing evidence has suggested an association between dietary magnesium intake and metabolic syndrome. However, previous research examining dietary magnesium intake and metabolic syndrome has produced mixed results. Our objective was to determine the relationship between dietary magnesium intake and metabolic syndrome in the adult population using a dose-response meta-analysis. We searched the PubMed, Embase and the Cochrane Library databases from August, 1965, to May, 2014. Observational studies reporting risk ratios with 95% confidence intervals (CIs) for metabolic syndrome in ≥ 3 categories of dietary magnesium intake levels were selected. The data extraction was performed independently by two authors, and the quality of the studies was evaluated using the Risk of Bias Assessment Tool for Nonrandomized Studies (RoBANS). Based on eight cross-sectional studies and two prospective cohort studies, the pooled relative risks of metabolic syndrome per 150 mg/day increment in magnesium intake was 0.88 (95% CI, 0.84-0.93; I(2) = 36.3%). The meta-regression model showed a generally linear, inverse relationship between magnesium intake (mg/day) and metabolic syndrome. This dose-response meta-analysis indicates that dietary magnesium intake is significantly and inversely associated with the risk of metabolic syndrome. However, randomized clinical trials will be necessary to address the issue of causality and to determine whether magnesium supplementation is effective for the prevention of metabolic syndrome.

Indexed as

Dose-Response Relationship, DrugHumansMagnesiumMetabolic SyndromeObservational Studies as TopicRisk AssessmentRisk FactorsMagnesium

Identifiers

PMID25533010
PMCPMC4277012
OpenAlexW2034087697

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.