Evidence map›Paper›PMID 25533005›Full record

SynthesisNutrients2014

The impact of anemia on child mortality: an updated review.

Samuel P Scott, Lenis P Chen-Edinboro, Laura E Caulfield, Laura E Murray-Kolb

Abstract readMeta-AnalysisReview
In one paragraph

Synthesis in Nutrients, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
115citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

115 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  8. Associations between metals and anemia indicator: mixed exposure effects and mediation analysis.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
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55 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Samuel P ScottDepartment of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802, USA. sps5032@psu.edu.
Lenis P Chen-EdinboroDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA. lchen78@jhu.edu.
Laura E CaulfieldProgram in Human Nutrition, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA. lcaulfi1@jhu.edu.
Laura E Murray-KolbDepartment of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802, USA. lem118@psu.edu.

Funding

PSYCHIATRIC EPIDEMIOLOGY TRAINING PROGRAMT32MH014592 · NIMH · JOHNS HOPKINS UNIVERSITY · PI HEATHER E VOLK, Peter P. Zandi · 1985 to 2026
$8.5M
NIMH NIH HHS T32 MH014592
6 · The paper itself

Abstract

Iron deficiency anemia and child mortality are public health problems requiring urgent attention. However, the degree to which iron deficiency anemia contributes to child mortality is unknown. Here, we utilized an exhaustive article search and screening process to identify articles containing both anemia and mortality data for children aged 28 days to 12 years. We then estimated the reduction in risk of mortality associated with a 1-g/dL increase in hemoglobin (Hb). Our meta-analysis of nearly 12,000 children from six African countries revealed a combined odds ratio of 0.76 (0.62-0.93), indicating that for each 1-g/dL increase in Hb, the risk of death falls by 24%. The feasibility of a 1-g/dL increase in Hb has been demonstrated via simple iron supplementation strategies. Our finding suggests that ~1.8 million deaths in children aged 28 days to five years could be avoided each year by increasing Hb in these children by 1 g/dL.

Indexed as

Child MortalityAfricaAnemia, Iron-DeficiencyChildChild, PreschoolDietary SupplementsHemoglobinsHumansInfantInfant, NewbornIron, DietaryPrevalenceHemoglobinsIron, Dietary

Identifiers

PMID25533005
PMCPMC4277007

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.