ArticleJournal of human evolution2015
The use of museum specimens with high-throughput DNA sequencers.
Article in Journal of human evolution, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.
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Who cites it
69 citing papers in PubMed.
- Eight quick tips for requesting materials from natural history collections.PLoS computational biology · 2026Article
- Whole genome sequencing of historical specimens from the world's largest fungal collection yields high-quality assemblies.The New phytologist · 2026Article
- De-extinction of the Northern white rhinoceros (Ceratotherium simum cottoni).The Journal of reproduction and development · 2026Review
- A Method for Preparing Morphologically Preserved Wildlife Fecal Specimens for Long-Term Ecological Studies.Ecology and evolution · 2026Article
- Short-read genome skimming enables molecular barcoding of old myxomycete collections.IMA fungus · 2026Article
- Unlocking natural history collections to improve eDNA reference databases and biodiversity monitoring.Bioscience · 2025Article
- Apristurus iterum, a new shark discovered based on egg case morphology and sequence data obtained from a formalin-fixed specimen.Journal of fish biology · 2025Article
- Sequestration and the Extended Museum Specimen: Effects of Time and Preparation Methodology.Journal of chemical ecology · 2025Article
- A century of anthropogenic perturbations impact genomic signatures of the iconic migratory Atlantic cod.Science advances · 2025Article
- Simple DNA extraction for museum beetle specimens to unlock genetic data from historical collections.MethodsX · 2025Article
- A High-Throughput Ancient DNA Extraction Method for Large-Scale Sample Screening.Molecular ecology resources · 2025Article
- Combination of Sample Preservation Approaches and DNA Extraction Methods for Long-Read Sequencing of Nudibranchs' Genomes.Ecology and evolution · 2025Article
- Article
- Challenges and Opportunities behind the Use ofPlants (Basel, Switzerland) · 2023Review
- Library preparation method and DNA source influence endogenous DNA recovery from 100-year-old avian museum specimens.Ecology and evolution · 2023Article
- DNA isolation and genome sequence of the 134-year-old holotype specimen ofEcology and evolution · 2023Article
- Article
- Review
- Developing the Protocol Infrastructure for DNA Sequencing Natural History Collections.Biodiversity data journal · 2023Article
- Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Natural history collections have long been used by morphologists, anatomists, and taxonomists to probe the evolutionary process and describe biological diversity. These biological archives also offer great opportunities for genetic research in taxonomy, conservation, systematics, and population biology. They allow assays of past populations, including those of extinct species, giving context to present patterns of genetic variation and direct measures of evolutionary processes. Despite this potential, museum specimens are difficult to work with because natural postmortem processes and preservation methods fragment and damage DNA. These problems have restricted geneticists' ability to use natural history collections primarily by limiting how much of the genome can be surveyed. Recent advances in DNA sequencing technology, however, have radically changed this, making truly genomic studies from museum specimens possible. We review the opportunities and drawbacks of the use of museum specimens, and suggest how to best execute projects when incorporating such samples. Several high-throughput (HT) sequencing methodologies, including whole genome shotgun sequencing, sequence capture, and restriction digests (demonstrated here), can be used with archived biomaterials.
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