Evidence map›Paper›PMID 25532531›Full record

ReviewLife (Basel, Switzerland)2014

Synthetic Biology: A Bridge between Artificial and Natural Cells.

Yunfeng Ding, Fan Wu, Cheemeng Tan

Abstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Engineering Cyborg Bacteria Through Intracellular Hydrogelation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  2. Stimuli-responsive vesicles as distributed artificial organelles for bacterial activation.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  3. Manufacturing polymeric porous capsules.Chemical communications (Cambridge, England) · 2022
    Review
  4. Review
  5. Toward synthetic life: Biomimetic synthetic cell communication.Current opinion in chemical biology · 2021
    Review
  6. USE OF ARTIFICIAL CELLS AS DRUG CARRIERS.Materials chemistry frontiers · 2021
    Article
  7. Review
  8. Article
  9. Article
  10. Artificial cells: from basic science to applications.Materials today (Kidlington, England) · 2016
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yunfeng DingDepartment of Biomedical Engineering, University of California Davis, One Shields Ave., Davis, CA 95616-5270, USA. yfding@ucdavis.edu.
Fan WuDepartment of Biomedical Engineering, University of California Davis, One Shields Ave., Davis, CA 95616-5270, USA. fwwu@ucdavis.edu.
Cheemeng TanDepartment of Biomedical Engineering, University of California Davis, One Shields Ave., Davis, CA 95616-5270, USA. cmtan@ucdavis.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artificial cells are simple cell-like entities that possess certain properties of natural cells. In general, artificial cells are constructed using three parts: (1) biological membranes that serve as protective barriers, while allowing communication between the cells and the environment; (2) transcription and translation machinery that synthesize proteins based on genetic sequences; and (3) genetic modules that control the dynamics of the whole cell. Artificial cells are minimal and well-defined systems that can be more easily engineered and controlled when compared to natural cells. Artificial cells can be used as biomimetic systems to study and understand natural dynamics of cells with minimal interference from cellular complexity. However, there remain significant gaps between artificial and natural cells. How much information can we encode into artificial cells? What is the minimal number of factors that are necessary to achieve robust functioning of artificial cells? Can artificial cells communicate with their environments efficiently? Can artificial cells replicate, divide or even evolve? Here, we review synthetic biological methods that could shrink the gaps between artificial and natural cells. The closure of these gaps will lead to advancement in synthetic biology, cellular biology and biomedical applications.

Identifiers

PMID25532531
PMCPMC4284483

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.