ArticleBMC genomics2014
Fine mapping of Rcr1 and analyses of its effect on transcriptome patterns during infection by Plasmodiophora brassicae.
Article in BMC genomics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers.
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89 citing papers in PubMed, 169 citations in OpenAlex.
- Genome-Wide Characterization and Expression Profiling of the Chitinase Gene Family in Radish (International journal of molecular sciences · 2026Article
- Loss of PMR4 callose synthase triggers jasmonic acid-dependent resistance to the clubroot disease in Arabidopsis and Brassica napus.The Plant cell · 2026Article
- A novel and efficient method for producing high-purity single protoplast-derived isolates ofFrontiers in microbiology · 2026Article
- Genetic and Epigenetic Mechanisms Underpinning Biotic Stress Resilience ofPlants (Basel, Switzerland) · 2025Review
- Identification and characterization ofHorticulture research · 2025Article
- Proteomics Integrated with Transcriptomics of Clubroot Resistant and SusceptibleInternational journal of molecular sciences · 2025Article
- Article
- Identification of Rcr12, a single dominant clubroot resistance gene near Rcr6 on chromosome B3 of Brassica nigra.BMC plant biology · 2025Article
- Clubroot resistant in cruciferous crops: recent advances in genes and QTLs identification and utilization.Horticulture research · 2025Article
- Metabolomic Profiling Identifies Key Metabolites and Defense Pathways inInternational journal of molecular sciences · 2025Article
- A chromosome-level reference genome facilitates the discovery of clubroot-resistant geneHorticulture research · 2025Article
- Identification of three novel QTL for resistance to highly aggressive Canadian strains ofFrontiers in plant science · 2025Article
- Genetic improvement of clubroot resistance in the recessive genic male sterile line YA001 inFrontiers in plant science · 2025Article
- Comprehensive review ofFrontiers in microbiology · 2025Review
- Genetic Mapping and Characterization of the Clubroot Resistance GeneInternational journal of molecular sciences · 2024Article
- Comparative Metabolome and Transcriptome Analysis Reveals the Defense Mechanism of Chinese Cabbage (International journal of molecular sciences · 2024Article
- Optimizing Clubroot Management and the Role of Canola Cultivar Mixtures.Pathogens (Basel, Switzerland) · 2024Review
- Resynthesizing Brassica napus with race specific resistance genes and race non-specific QTLs to multiple races of Plasmodiophora brassicae.Scientific reports · 2024Article
- Resilience of Canola toPlants (Basel, Switzerland) · 2024Article
- A CRISPR/Cas9-based vector system enables the fast breeding of selection-marker-free canola with Rcr1-rendered clubroot resistance.Journal of experimental botany · 2024Article
29 more citing papers are in PubMed but not listed here.
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe protist Plasmodiophora brassicae is a biotrophic soil-borne pathogen that causes clubroot on Brassica crops worldwide. Clubroot disease is a serious threat to the 8 M ha of canola (Brassica napus) grown annually in western Canada. While host resistance is the key to clubroot management, sources of resistance are limited.
resultsTo identify new sources of clubroot resistance (CR), we fine mapped a CR gene (Rcr1) from B. rapa ssp. chinensis to the region between 24.26 Mb and 24.50 Mb on the linkage group A03, with several closely linked markers identified. Transcriptome analysis was conducted using RNA sequencing on a segregating F1 population inoculated with P. brassicae, with 2,212 differentially expressed genes (DEGs) identified between plants carrying and not carrying Rcr1. Functional annotation of these DEGs showed that several defense-related biological processes, including signaling and metabolism of jasmonate and ethylene, defensive deposition of callose and biosynthesis of indole-containing compounds, were up-regulated significantly in plants carrying Rcr1 while genes involved in salicylic acid metabolic and signaling pathways were generally not elevated. Several DEGs involved in metabolism potentially related to clubroot symptom development, including auxin biosynthesis and cell growth/development, showed significantly lower expression in plants carrying Rcr1.
conclusionThe CR gene Rcr1 and closely linked markers will be highly useful for breeding new resistant canola cultivars. The identification of DEGs between inoculated plants carrying and not carrying Rcr1 is an important step towards understanding of specific metabolic/signaling pathways in clubroot resistance mediated by Rcr1. This information may help judicious use of CR genes with complementary resistance mechanisms for durable clubroot resistance.
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