ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2015
Staphylococcus pseudintermedius can be misdiagnosed as Staphylococcus aureus in humans with dog bite wounds.
Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.
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Who cites it
65 citing papers in PubMed, 1 synthesis or guideline pooled it, 111 citations in OpenAlex.
- Nasal Staphylococcus aureus and S. pseudintermedius carriage in healthy dogs and cats: a systematic review of their antibiotic resistance, virulence and genetic lineages of zoonotic relevance.Journal of applied microbiology · 2022Pooled it
- Longitudinal Epidemiology of Coagulase-Positive Staphylococcal Species Recovered from Humans, Pets, and Household Environments.Antibiotics (Basel, Switzerland) · 2026Article
- Molecular Characterization and Comparative Genomics of TwoVeterinary sciences · 2026Article
- Diversity among isolates of Staphylococcus intermedius group from Pacific marine mammals of Southern California.PloS one · 2026Article
- Comparative phylogenetic, antimicrobial resistance, and clinical characterization of human spondylodiscitis-associatedFrontiers in microbiology · 2026Article
- Isolation and Molecular Characterization of Three Staphylococcus pseudintermedius Strains from Dogs and Humans in Egypt.Current microbiology · 2025Article
- Antibacterial Activity of Clove Essential Oil (Pathogens (Basel, Switzerland) · 2025Article
- Article
- A novel case of Staphylococcus pseudintermedius aortitis.Access microbiology · 2025Article
- Occurrence ofVeterinary world · 2024Article
- Genomic Analyses of Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2024Article
- Methicillin Resistance Elements in the Canine PathogenAntibiotics (Basel, Switzerland) · 2024Article
- Epidemiologic case investigation on the zoonotic transmission of Methicillin-resistant Staphylococcus pseudintermedius among dogs and their owners.Journal of infection and public health · 2023Article
- Diagnostic and commensal Staphylococcus pseudintermedius genomes reveal niche adaptation through parallel selection of defense mechanisms.Nature communications · 2023Article
- Virulence Mechanisms of Staphylococcal Animal Pathogens.International journal of molecular sciences · 2023Review
- Antimicrobial ResistantPathogens (Basel, Switzerland) · 2023Article
- Genomic Features of Antimicrobial Resistance inInternational journal of molecular sciences · 2023Article
- Cheilitis in an atopic dermatitis patient associated with co-infection of Staphylococcus pseudintermedius and Staphylococcus aureus.BMC microbiology · 2023Article
- Complete Genome Sequences of 11 Staphylococcus pseudintermedius Isolates from Dogs in the United States.Microbiology resource announcements · 2023Article
- Activity of Patchouli and Tea Tree Essential Oils against Staphylococci Isolated from Pyoderma in Dogs and Their Synergistic Potential with Gentamicin and Enrofloxacin.Animals : an open access journal from MDPI · 2023Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this study was to investigate whether S. pseudintermedius is misdiagnosed as S. aureus by clinical laboratories when isolated from humans with dog bite wounds. In addition, we attempted to determine whether S. pseudintermedius isolates related to dog bite wounds share phenotypic and genotypic traits. S. pseudintermedius was identified by PCR targeting the nuc gene. Isolates were tested for antibiotic susceptibility using VetMIC GP-mo microdilution panels. The occurrence of genes encoding leukocidins, exfoliatins, pyrogenic toxin superantigens and enterotoxins was determined by PCR. The relatedness of S. pseudintermedius isolates was investigated using Multi Locus Sequence Typing (MLST). Out of 101 isolates defined as S. aureus by human clinical microbiology laboratories, 13 isolates were re-identified as S. pseudintermedius and one isolate was confirmed to carry the mecA gene, i.e. methicillin-resistant (MRSP). The MRSP isolate was also defined as multi-resistant. Two methicillin-susceptible S. pseudintermedius isolates were also multi-resistant and five were susceptible to all antibiotics tested. With the exception of three S. pseudintermedius isolates belonging to multi locus sequence type (MLST) 158, all the isolates belonged to unique STs. All isolates contained lukS/F-I, siet and se-int, and expA were identified in two isolates and expB and sec canine-sel in one isolate respectively. S. pseudintermedius is frequently misdiagnosed as S. aureus from humans with dog bite wounds showing that it can act as an opportunistic pathogen in humans. No common phenotypic and genotypic traits shared by the S. pseudintermedius isolates could be identified.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.