ReviewParasite (Paris, France)2014
Non-surgical and non-chemical attempts to treat echinococcosis: do they work?
Review in Parasite (Paris, France), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 58 citations in OpenAlex.
- Non-Surgical Exceptional Management of Inoperable Hydatidosis with Radiotherapy: Case Report and Review of Literature.The American journal of tropical medicine and hygiene · 2025Review
- Investigating the Therapeutic Effects of Albendazole, Mebendazole, and Praziquantel Nanocapsules in Hydatid Cyst-Infected Mice.Pathogens (Basel, Switzerland) · 2025Article
- Primary spinal extradural hydatid cyst: a rare cause of compressive neuropathy in a pediatric patient.Annals of medicine and surgery (2012) · 2025Article
- Diagnosis and treatment modalities of hilar biliary duct stricture in hepatic cystic echinococcosis after endocystectomy.Parasite (Paris, France) · 2021Article
- Laparoscopic hepatectomy for the treatment of hepatic alveolar echinococcosis.Parasite (Paris, France) · 2021Article
- Cardiac hydatid cyst in the right ventricle: An unusual case at a rare site.Journal of Taibah University Medical Sciences · 2020Article
- International consensus on terminology to be used in the field of echinococcoses.Parasite (Paris, France) · 2020Article
- Laparoscopic Management of Initially Unrecognized Splenic Hydatid Cysts: A Case Report and Review of the Literature.Medicina (Kaunas, Lithuania) · 2019Review
- Ultrastructural changes in hydatid cyst walls obtained from human cases, exposed to different therapeutic approaches.Parasitology research · 2019Article
- Evaluation of clinical, diagnostic and treatment aspects in hydatid disease: analysis of an 8-year experience.African health sciences · 2019Article
- High-intensity focused ultrasound ablation: a non-surgical approach to treat advanced and complicated liver alveococcosis.Journal of medical ultrasonics (2001) · 2019Article
- Echinococcosis: Advances in the 21st Century.Clinical microbiology reviews · 2019Review
- Ultrasound and Cystic Echinococcosis.Ultrasound international open · 2018Review
- Case Report: Role of Interventional Radiology in the Management of Patients with Alveolar Echinococcus: Successful Management of Three Cases.The American journal of tropical medicine and hygiene · 2018Article
- The choose of different surgical therapies of hepatic alveolar echinococcosis: A single-center retrospective case-control study.Medicine · 2018Article
- Treatment of Hepatic Hydatid Cyst in a 7-Year-Old Boy Using a New Type of Radiofrequency Ablation Electrode.The American journal of case reports · 2017Article
- Presentation of secondary parasitic infection 37 years after primary infection.Journal of surgical case reports · 2017Article
- Nanosecond pulsed electric field (nsPEF) disrupts the structure and metabolism of human Echinococcus granulosus protoscolex in vitro with a dose effect.Parasitology research · 2017Article
- Superinfection of a Dead Hepatic Echinococcal Cyst with a Cutaneous Fistulization.Case reports in radiology · 2017Article
- Scolicidal and apoptotic activities of albendazole sulfoxide and albendazole sulfoxide-loaded PLGA-PEG as a novel nanopolymeric particle against Echinococcus granulosus protoscoleces.Parasitology research · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cystic echinococcosis (CE) and alveolar echinococcosis (AE) are chronic, complex and neglected diseases. Their treatment depends on a number of factors related to the lesion, setting and patient. We performed a literature review of curative or palliative non-surgical, non-chemical interventions in CE and AE. In CE, some of these techniques, like radiofrequency thermal ablation (RFA), were shelved after initial attempts, while others, such as High-Intensity Focused Ultrasound, appear promising but are still in a pre-clinical phase. In AE, RFA has never been tested, however, radiotherapy or heavy-ion therapies have been attempted in experimental models. Still, application to humans is questionable. In CE, although prospective clinical studies are still lacking, therapeutic, non-surgical drainage techniques, such as PAIR (puncture, aspiration, injection, re-aspiration) and its derivatives, are now considered a useful option in selected cases. Finally, palliative, non-surgical drainage techniques such as US- or CT-guided percutaneous biliary drainage, centro-parasitic abscesses drainage, or vascular stenting were performed successfully. Recently, endoscopic retrograde cholangiopancreatography (ERCP)-associated techniques have become increasingly used to manage biliary fistulas in CE and biliary obstructions in AE. Development of pre-clinical animal models would allow testing for AE techniques developed for other indications, e.g. cancer. Prospective trials are required to determine the best use of PAIR, and associated procedures, and the indications and techniques of palliative drainage.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.