Evidence map›Paper›PMID 25531059›Full record

ArticleForensic science international. Genetics2015

Feline mitochondrial DNA sampling for forensic analysis: when enough is enough!

Robert A Grahn, Hasan Alhaddad, Paulo C Alves, Ettore Randi, Nashwa E Waly, Leslie A Lyons

Abstract readEvaluation Study
In one paragraph

Article in Forensic science international. Genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Mitochondrial Control Region Database of Hungarian Fallow Deer (Animals : an open access journal from MDPI · 2024
    Article
  2. The Revolution of Animal Genomics in Forensic Sciences.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Robert A GrahnDepartment of Population Health and Reproduction, School of Veterinary Medicine, University of California - Davis, Davis, CA 95616, USA. Electronic address: ragrahn@ucdavis.edu.
Hasan AlhaddadDepartment of Population Health and Reproduction, School of Veterinary Medicine, University of California - Davis, Davis, CA 95616, USA.
Paulo C AlvesCIBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos and Departamento de Biologia da Faculdade de Ciências do Porto, Universidade do Porto, Portugal.
Ettore RandiLaboratorio di Genetica, ISPRA, Istituto Superiore per la Protezione e la Ricerca Ambientale, Via Cà Fornacetta 9, 40064 Ozzano dell'Emilia, BO, Italy; Department 18/Section of Environmental Engineering, Aalborg University, Sohngårdsholmsvej 57, 9000 Aalborg, Denmark.
Nashwa E WalyDepartment of Animal Medicine, Faculty of Veterinary Medicine, Assiut University, 71526 Assiut, Egypt.
Leslie A LyonsDepartment of Population Health and Reproduction, School of Veterinary Medicine, University of California - Davis, Davis, CA 95616, USA.

Funding

Genetic Mapping Resources for Common Mammalian DiseasesR24RR016094 · NCRR · UNIVERSITY OF CALIFORNIA DAVIS · PI LYONS, LESLIE A · 2002 to 2011
$3.0M
Genetic Mapping Resources for Common Mammalian DiseasesR24OD010928 · OD · UNIVERSITY OF MISSOURI-COLUMBIA · PI LYONS, LESLIE A · 2012 to 2015
$911k
NCRR NIH HHS R24 RR016094NCRR NIH HHS R24 RR016094R24NIH HHS R24 OD010928NIH HHS R24OD010928
6 · The paper itself

Abstract

Pet hair has a demonstrated value in resolving legal issues. Cat hair is chronically shed and it is difficult to leave a home with cats without some level of secondary transfer. The power of cat hair as an evidentiary resource may be underused because representative genetic databases are not available for exclusionary purposes. Mitochondrial control region databases are highly valuable for hair analyses and have been developed for the cat. In a representative worldwide data set, 83% of domestic cat mitotypes belong to one of twelve major types. Of the remaining 17%, 7.5% are unique within the published 1394 sample database. The current research evaluates the sample size necessary to establish a representative population for forensic comparison of the mitochondrial control region for the domestic cat. For most worldwide populations, randomly sampling 50 unrelated local individuals will achieve saturation at 95%. The 99% saturation is achieved by randomly sampling 60-170 cats, depending on the numbers of mitotypes available in the population at large. Likely due to the recent domestication of the cat and minimal localized population substructure, fewer cats are needed to meet mitochondria DNA control region database practical saturation than for humans or dogs. Coupled with the available worldwide feline control region database of nearly 1400 cats, minimal local sampling will be required to establish an appropriate comparative representative database and achieve significant exclusionary power.

Indexed as

AnimalsCatsDatabases, Nucleic AcidDNA FingerprintingDNA, MitochondrialForensic GeneticsHairMitochondriaPetsDNA, MitochondrialControl regionDomestic catFelis silvestris catusForensic ScienceMitotypemtDNA

Identifiers

PMID25531059
PMCPMC4400830

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.