Evidence map›Paper›PMID 25530979›Full record

ArticleJournal of biological methods2014

A stepwise procedure to test contractility and susceptibility to injury for the rodent quadriceps muscle.

Stephen J P Pratt, Richard M Lovering

Abstract read
In one paragraph

Article in Journal of biological methods, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. In vivo Measurement of Knee Extensor Muscle Function in Mice.Journal of visualized experiments : JoVE · 2021
    Article
  4. Article
  5. Article
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  9. Article
  10. Intrathecal gene therapy rescues a model of demyelinating peripheral neuropathy.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
  11. A method to test contractility of the supraspinatus muscle in mouse, rat, and rabbit.Journal of applied physiology (Bethesda, Md. : 1985) · 2016
    Article
  12. In Vivo Assessment of Muscle Contractility in Animal Studies.Methods in molecular biology (Clifton, N.J.) · 2016
    Article
  13. SERCA1 overexpression minimizes skeletal muscle damage in dystrophic mouse models.American journal of physiology. Cell physiology · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Stephen J P PrattDepartment of Orthopaedics, University of Maryland School of Medicine, Baltimore, MD.
Richard M LoveringDepartment of Orthopaedics, University of Maryland School of Medicine, Baltimore, MD.

Funding

Mechanisms of Force Loss in Injured and Dystrophic Skeletal MuscleR01AR059179 · NIAMS · UNIVERSITY OF MARYLAND BALTIMORE · PI LOVERING, RICHARD M · 2010 to 2014
$1.4M
NIAMS NIH HHS R01 AR059179
6 · The paper itself

Abstract

In patients with muscle injury or muscle disease, assessment of muscle damage is typically limited to clinical signs, such as tenderness, strength, range of motion, and more recently, imaging studies. Biological markers can also be used in measuring muscle injury, such as increased creatine kinase levels in the blood, but these are not always correlated with loss in muscle function (i.e. loss of force production). This is even true of histological findings from animals, which provide a "direct measure" of damage, but do not account for loss of function. The most comprehensive measure of the overall health of the muscle is contractile force. To date, animal models testing contractile force have been limited to the muscle groups moving the ankle. Here we describe an

Indexed as

contractile functioninjurylengthening contractionquadricepsrecoveryskeletal musclespecific forcetorque

Identifiers

PMID25530979
PMCPMC4269275

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.