Evidence map›Paper›PMID 25530940›Full record

ArticlePreventive medicine reports2014

Adverse events Following Computed Tomographic Colonography compared to Optical Colonoscopy in the Elderly.

Hanna M Zafar, Michael O Harhay, Jianing Yang, Katrina Armstron

Open access · goldAbstract read
In one paragraph

Article in Preventive medicine reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 4 pooled it
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 4 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Guideline
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Hanna M ZafarDepartment of Radiology Hospital of the University of Pennsylvania 3400 Spruce Street Philadelphia, PA 19104 ; Leonard Davis Institute of Health Economics University of Pennsylvania Colonial Penn Center, 3641 Locust Walk Philadelphia, PA 19104-6218 Philadelphia, United States.
Michael O HarhayDepartment of Medicine Hospital of the University of Pennsylvania 3400 Spruce Street Philadelphia, PA 19104.
Jianing YangDepartment of Medicine Hospital of the University of Pennsylvania 3400 Spruce Street Philadelphia, PA 19104.
Katrina ArmstronDepartment of Medicine Massachusetts General Hospital 55 Fruit Street-GRB 740 Boston, MA 02114.
Hospital of the University of Pennsylvania · USMassachusetts General Hospital · US

Funding

Career Development in Comparative Effectiveness ResearchKM1CA156715 · NCI · UNIVERSITY OF PENNSYLVANIA · PI METLAY, JOSHUA P · 2010 to 2010
$2.5M
NCI NIH HHS KM1 CA156715
6 · The paper itself

Abstract

objectiveTo evaluate gastrointestinal and cardiovascular adverse event risks associated with optical colonoscopy (OC) among Medicare outpatients who received computed tomography colonography (CTC) as their initial method of colorectal evaluation.

methodsMedicare claims were compared between 6,114 outpatients ≥ 66 years who received initial CTC and 149,202 outpatients who received initial OC between January 2007 and December 2008. OC patients were matched on county of residence and year of evaluation. Outcomes included lower gastrointestinal bleeding, gastrointestinal perforation, other gastrointestinal events and cardiovascular events resulting in an emergency department visit or hospitalization within 30 days.

resultsAmong 1,000 outpatients undergoing initial CTC, 12.4 experienced lower gastrointestinal bleeding, 0.7 perforation, 18.0 other gastrointestinal events and 45.5 cardiovascular events within 30 days. After multivariate adjustment, risks of lower gastrointestinal bleeding, other gastrointestinal events and cardiovascular events were higher with initial OC than CTC, with or without subsequent OC (OR 1.91 95CI [1.47,2.49], OR 1.35 95CI [1.07,1.69] and OR 1.38 95CI [1.18,1.62], respectively); however, perforation risk did not differ (p=0.10). This pattern is similar in older and symptomatic populations.

conclusionRates of gastrointestinal bleeding, other gastrointestinal events and cardiovascular events are lower following initial CTC than OC, but rates of perforation do not differ.

Identifiers

PMID25530940
PMCPMC4266938
OpenAlexW2061082916

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.