Evidence map›Paper›PMID 25530791›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2014

An alternative to current therapies of functional dyspepsia: self-administrated transcutaneous electroacupuncture improves dyspeptic symptoms.

Ting Ji, Xueliang Li, Lin Lin, Liuqin Jiang, Meifeng Wang, Xiaopin Zhou, Ranran Zhang, Jiande Dz Chen

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Noninvasive electrical neuromodulation for gastrointestinal motility disorders.Expert review of gastroenterology & hepatology · 2023
    Review
  6. Review
  7. Neuromodulation for functional upper gastrointestinal diseases.Gut microbiota and integrative wellness · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Non-pharmacological Approach in the Management of Functional Dyspepsia.Journal of neurogastroenterology and motility · 2020
    Review
  13. Article
  14. Use of Bioelectronics in the Gastrointestinal Tract.Cold Spring Harbor perspectives in medicine · 2019
    Review
  15. Article
  16. EA at PC6 Promotes Gastric Motility: Role of Brainstem Vagovagal Neurocircuits.Evidence-based complementary and alternative medicine : eCAM · 2019
    Article
  17. Complementary and Alternative Therapies for Functional Gastrointestinal Diseases 2016.Evidence-based complementary and alternative medicine : eCAM · 2017
    Article
  18. Effects of Transcutaneous Electrical Acustimulation on Refractory Gastroesophageal Reflux Disease.Evidence-based complementary and alternative medicine : eCAM · 2016
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Ting JiDivision of Gastroenterology, Department of Gastroenterology, First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China.
Xueliang LiDivision of Gastroenterology, Department of Gastroenterology, First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China.
Lin LinDivision of Gastroenterology, Department of Gastroenterology, First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China.
Liuqin JiangDivision of Gastroenterology, Department of Gastroenterology, First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China.
Meifeng WangDivision of Gastroenterology, Department of Gastroenterology, First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China.
Xiaopin ZhouDivision of Gastroenterology, Department of Gastroenterology, First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China.
Ranran ZhangDivision of Gastroenterology, Department of Gastroenterology, First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China.
Jiande Dz ChenDivision of Gastroenterology and Hepatology, Johns Hopkins Medicine, Baltimore, MD 21224, USA.
Nanjing Medical University · CNJohns Hopkins Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Functional dyspepsia is of high prevalence with little treatment options. The aim of this study was to develop a new treatment method using self-management transcutaneous electroacupuncture (TEA) for functional dyspepsia (FD). Twenty-eight patients with FD were enrolled and underwent a crossover clinical trial with 2-week TEA at ST36 and PC6 and 2-week sham-TEA at nonacupuncture sham-points. Questionnaires were used to assess symptoms of dyspepsia and quality of life. Physiological testing included gastric emptying and electrogastrography. It was found that (1) TEA but not sham-TEA significantly improved dyspeptic symptoms and 4 domains in quality of life; improvement was also noted in self-rated anxiety and depression scores; (2) gastric emptying was significantly and substantially increased with 2-week TEA but not sham-TEA; and (3) gastric accommodation was also improved with TEA but not sham-TEA, reflected as increased ingested nutrient volumes at the levels of satiety and maximum tolerance. These findings suggest a therapeutic potential of self-administrated TEA method for functional dyspepsia, possibly attributed to improvement in gastric motility.

Identifiers

PMID25530791
PMCPMC4230003
OpenAlexW2132896998

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.