ArticleCurrent opinion in solid state & materials science2014
Materials approaches for modulating neural tissue responses to implanted microelectrodes through mechanical and biochemical means.
Article in Current opinion in solid state & materials science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Identifying Heterogeneous Micromechanical Properties of Biological Tissues via Physics-Informed Neural Networks.Small methods · 2025Article
- Article
- Amorphous SiC Thin Films Deposited by Plasma-Enhanced Chemical Vapor Deposition for Passivation in Biomedical Devices.Materials (Basel, Switzerland) · 2024Review
- Chronic Stability of Local Field Potentials Using Amorphous Silicon Carbide Microelectrode Arrays Implanted in the Rat Motor Cortex.Micromachines · 2023Article
- Engineering strategies towards overcoming bleeding and glial scar formation around neural probes.Cell and tissue research · 2022Review
- Flexible Neural Probes with Optical Artifact-Suppressing Modification and Biofriendly Polypeptide Coating.Micromachines · 2022Article
- The Long-Term Stability of Intracortical Microstimulation and the Foreign Body Response Are Layer Dependent.Frontiers in neuroscience · 2022Article
- The Future of Neuroscience: Flexible and Wireless Implantable Neural Electronics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Review
- Hybrid Electrical and Optical Neural Interfaces.Journal of micromechanics and microengineering : structures, devices, and systems · 2021Article
- Advances in Carbon-Based Microfiber Electrodes for Neural Interfacing.Frontiers in neuroscience · 2021Review
- Immunohistological and Ultrastructural Study of the Inflammatory Response to Perforated Polyimide Cortical Implants: Mechanisms Underlying Deterioration of Electrophysiological Recording Quality.Frontiers in neuroscience · 2020Article
- Bioactive Neuroelectronic Interfaces.Frontiers in neuroscience · 2019Review
- Genetic Modulation at the Neural Microelectrode Interface: Methods and Applications.Micromachines · 2018Article
- On the use of Parylene C polymer as substrate for peripheral nerve electrodes.Scientific reports · 2018Article
- Tissue-Engineered Peripheral Nerve Interfaces.Advanced functional materials · 2018Article
- Article
- A Mosquito Inspired Strategy to Implant Microprobes into the Brain.Scientific reports · 2018Article
- Biomimetic extracellular matrix coatings improve the chronic biocompatibility of microfabricated subdural microelectrode arrays.PloS one · 2018Article
- Microelectrode implantation in motor cortex causes fine motor deficit: Implications on potential considerations to Brain Computer Interfacing and Human Augmentation.Scientific reports · 2017Article
- Review: Human Intracortical Recording and Neural Decoding for Brain-Computer Interfaces.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Implantable intracortical microelectrodes face an uphill struggle for widespread clinical use. Their potential for treating a wide range of traumatic and degenerative neural disease is hampered by their unreliability in chronic settings. A major factor in this decline in chronic performance is a reactive response of brain tissue, which aims to isolate the implanted device from the rest of the healthy tissue. In this review we present a discussion of materials approaches aimed at modulating the reactive tissue response through mechanical and biochemical means. Benefits and challenges associated with these approaches are analyzed, and the importance of multimodal solutions tested in emerging animal models are presented.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.