Evidence map›Paper›PMID 25530675›Full record

Trial reportBehavioural neurology2014

Effect of anodal transcranial direct current stimulation on autism: a randomized double-blind crossover trial.

Anuwat Amatachaya, Narong Auvichayapat, Niramol Patjanasoontorn, Chanyut Suphakunpinyo, Niran Ngernyam, Benchaporn Aree-Uea, Keattichai Keeratitanont, Paradee Auvichayapat

2 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Behavioural neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 53 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03947086 naunknown statusnot on this mapstarted 2018, after this paper: background citation

Transcranial Direct Current Stimulation for Cognitive Rehabilitation of Children With Autistic Spectrum Disorders

TypeinterventionalSponsorFederal University of ParaíbaRan2018 to 2019Enrolled16ConditionsAutistic Disorders SpectrumArmsTranscranial Direct Current Stimulation (TDCS)- Active, Transcranial Direct Current Stimulation (TDCS)- Sham, Cognitive Training
NCT04490187 naunknown statusnot on this mapstarted 2018, after this paper: background citation

tDCS and Motor Learning in Children With DCD

TypeinterventionalSponsorUniversity of British ColumbiaRan2018 to 2021Enrolled14ConditionsDevelopmental Coordination DisorderArmsMotor Learning
3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  8. Multisession tDCS combined with intrastimulation training improves emotion recognition in adolescents with autism spectrum disorder.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2024
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  20. The use of noninvasive brain stimulation techniques in autism spectrum disorder.Autism research : official journal of the International Society for Autism Research · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anuwat AmatachayaDepartment of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0002-8629-5799
Narong AuvichayapatDepartment of Pediatrics, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0001-6967-8600
Niramol PatjanasoontornDepartment of Psychiatry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Chanyut SuphakunpinyoDepartment of Pediatrics, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0001-6170-0332
Niran NgernyamDepartment of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0003-1387-9432
Benchaporn Aree-UeaDepartment of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0002-6966-3211
Keattichai KeeratitanontDepartment of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Paradee AuvichayapatDepartment of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0003-1829-2753

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to evaluate the Childhood Autism Rating Scale (CARS), Autism Treatment Evaluation Checklist (ATEC), and Children's Global Assessment Scale (CGAS) after anodal transcranial direct current stimulation (tDCS) in individuals with autism. Twenty patients with autism received 5 consecutive days of both sham and active tDCS stimulation (1 mA) in a randomized double-blind crossover trial over the left dorsolateral prefrontal cortex (F3) for 20 minutes in different orders. Measures of CARS, ATEC, and CGAS were administered before treatment and at 7 days posttreatment. The result showed statistical decrease in CARS score (P < 0.001). ATEC total was decreased from 67.25 to 58 (P < 0.001). CGAS was increased at 7 days posttreatment (P = 0.042). Our study suggests that anodal tDCS over the F3 may be a useful clinical tool in autism.

Indexed as

Transcranial Direct Current StimulationAutistic DisorderChildChild, PreschoolCross-Over StudiesDouble-Blind MethodHumansMalePrefrontal CortexPsychiatric Status Rating Scales

Identifiers

PMID25530675
PMCPMC4230001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.