Evidence map›Paper›PMID 25530636›Full record

ArticleStat2014

A Model-Free Machine Learning Method for Risk Classification and Survival Probability Prediction.

Yuan Geng, Wenbin Lu, Hao Helen Zhang

Abstract read
In one paragraph

Article in Stat, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yuan GengBoehringer Ingelheim International Trading Co., Ltd., Shanghai, 200040, P. R. China.
Wenbin LuDepartment of Statistics, North Carolina State University, Raleigh, NC 27695, USA.
Hao Helen ZhangDepartment of Mathematics, University of Arizona, Tucson, AZ 85721, USA.

Funding

Statistical Methods for Cancer Clinical TrialsP01CA142538 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVIDIAN, MARIE, KOSOROK, MICHAEL R · 2010 to 2019
$21.3M
Flexible Statistical Methods for Complex Survival Data in Biomedical StudiesR01CA140632 · NCI · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI LU, WENBIN · 2010 to 2013
$795k
NCI NIH HHS P01 CA142538NCI NIH HHS R01 CA140632
6 · The paper itself

Abstract

Risk classification and survival probability prediction are two major goals in survival data analysis since they play an important role in patients' risk stratification, long-term diagnosis, and treatment selection. In this article, we propose a new model-free machine learning framework for risk classification and survival probability prediction based on weighted support vector machines. The new procedure does not require any specific parametric or semiparametric model assumption on data, and is therefore capable of capturing nonlinear covariate effects. We use numerous simulation examples to demonstrate finite sample performance of the proposed method under various settings. Applications to a glioma tumor data and a breast cancer gene expression survival data are shown to illustrate the new methodology in real data analysis.

Indexed as

Model-freeRisk classificationSupport vector machinesSurvival probability prediction

Identifiers

PMID25530636
PMCPMC4266578

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.