ArticleThe Hastings Center report
SUPPORT and the Ethics of Study Implementation: Lessons for Comparative Effectiveness Research from the Trial of Oxygen Therapy for Premature Babies.
Article in The Hastings Center report. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Ethical challenges in first-in-human trials of the artificial placenta and artificial womb: not all technologies are created equally, ethically.Journal of perinatology : official journal of the California Perinatal Association · 2023Review
- The evolution of mean arterial pressure in critically ill patients on vasopressors before and during a trial comparing a specific mean arterial pressure target to usual care.BMC anesthesiology · 2022Observational
- Article
- Article
- Ethical issues in pragmatic trials of "standard-of-care" interventions in learning health care systems.Learning health systems · 2018Article
- Comparative effectiveness research: what to do when experts disagree about risks.BMC medical ethics · 2017Article
- Ethical and clinical safety considerations in the design of an effectiveness trial: A comparison of buprenorphine versus naltrexone treatment for opioid dependence.Contemporary clinical trials · 2016Article
- Recent controversies on comparative effectiveness research investigations: Challenges, opportunities, and pitfalls.Seminars in perinatology · 2016Article
- Parental and staff perspectives of NICU research procedures.BMC pediatrics · 2016Article
- Ethical complexities in standard of care randomized trials: A case study of morning versus nighttime dosing of blood pressure drugs.Clinical trials (London, England) · 2015Article
- The ethics and regulatory landscape of including vulnerable populations in pragmatic clinical trials.Clinical trials (London, England) · 2015Article
- Mapping the Ethics of Translational Genomics: Situating Return of Results and Navigating the Research-Clinical Divide.The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics · 2015Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The design of SUPPORT has been widely misunderstood. This confusion has driven much of the debate about the trial - and threatens the whole enterpise of comparative effectiveness research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.