ArticleEmerging infectious diseases2015
Molecular epidemiology and genetic diversity of Orientia tsutsugamushi from patients with scrub typhus in 3 regions of India.
Article in Emerging infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 4 of them syntheses that pooled it.
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Who cites it
55 citing papers in PubMed, 4 syntheses or guidelines pooled it, 106 citations in OpenAlex.
- Burden of scrub typhus in north-eastern region of India: A systematic review and meta-regression analysis.The Indian journal of medical research · 2026Pooled it
- Spatiotemporal epidemiology and clinical manifestations of two decades of scrub typhus in India: a systematic review and meta-analysis.BMJ global health · 2025Pooled it
- The burden of scrub typhus in India: A systematic review.PLoS neglected tropical diseases · 2021Pooled it
- The validity of diagnostic cut-offs for commercial and in-house scrub typhus IgM and IgG ELISAs: A review of the evidence.PLoS neglected tropical diseases · 2019Pooled it
- Transformation and allelic exchange inmBio · 2026Article
- Transformation and allelic exchange inbioRxiv : the preprint server for biology · 2026Article
- Nasopharyngeal Swabs forPathogens (Basel, Switzerland) · 2026Article
- Seasonal and spatial trends of rickettsioses in Sri Lanka (2009-2023): Spatio-temporal analysis and climate-linked modeling.PloS one · 2026Article
- A New Gilliam Genotypic Variant ofMicroorganisms · 2025Article
- Diagnostic heterogeneity in scrub typhus serology: A scoping review of IFA thresholds and regional standardisation needs (2005-2024).PLoS neglected tropical diseases · 2025Article
- Orientia tsutsugamushi modulates p53, the cell cycle, and genotoxicity to maintain its intracellular niche.Nature communications · 2025Article
- Scrub Typhus With an Unknown Source of Infection.Cureus · 2025Article
- Article
- A Novel Genotype ofMicroorganisms · 2025Article
- A longitudinal molecular surveillance of genetic heterogeneity ofFrontiers in microbiology · 2025Article
- Analysis of outer membrane protein fromBioinformation · 2025Article
- Orientia tsutsugamushi Ank5 promotes NLRC5 cytoplasmic retention and degradation to inhibit MHC class I expression.Nature communications · 2024Article
- Orientia tsutsugamushi: An Unusual Intracellular Bacteria-Adaptation Strategies, Available Antibiotics, and Alternatives for Treatment.Current microbiology · 2024Review
- Molecular detection of Orientia tsutsugamushi in ectoparasites & their small mammal hosts captured from scrub typhus endemic areas in Madurai district, India.The Indian journal of medical research · 2024Article
- Reverse vaccinology and immunoinformatics approach to design a chimeric epitope vaccine againstHeliyon · 2024Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
Abstract
Scrub typhus, an acute febrile illness that is widespread in the Asia-Pacific region, is caused by the bacterium Orientia tsutsugamushi, which displays high levels of antigenic variation. We conducted an investigation to identify the circulating genotypes of O. tsutsugamushi in 3 scrub typhus-endemic geographic regions of India: South India, Northern India, and Northeast India. Eschar samples collected during September 2010-August 2012 from patients with scrub typhus were subjected to 56-kDa type-specific PCR and sequencing to identify their genotypes. Kato-like strains predominated (61.5%), especially in the South and Northeast, followed by Karp-like strains (27.7%) and Gilliam and Ikeda strains (2.3% each). Neimeng-65 genotype strains were also observed in the Northeast. Clarifying the genotypic diversity of O. tsutsugamushi in India enhances knowledge of the regional diversity among circulating strains and provides potential resources for future region-specific diagnostic studies and vaccine development.
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